Universal screening for cytomegalovirus infection in early pregnancy

Universal Screening Program for Cytomegalovirus Infection in the First Trimester of Pregnancy: A Multicentre Pilot Study in the Area of Barcelona (CITEMB Study)

Observational Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina · NCT05699421

This study is testing a new screening program for cytomegalovirus in pregnant women during their first trimester to see how well it works and if it can help prevent problems for babies.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
Ages16 Years to 45 Years
SexFemale
SponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina Academic / other
Locations1 site (Badalona)
Trial IDNCT05699421 on ClinicalTrials.gov

What this trial studies

This pilot study evaluates a universal cytomegalovirus (CMV) screening program for pregnant women in their first trimester in Catalonia, Spain. The study aims to assess the acceptance rate of CMV screening, the incidence of primary CMV infections, and the rates of vertical transmission and associated fetal sequelae. Additionally, it will analyze the economic implications of implementing such a screening program in primary care settings. The findings will help inform future public health strategies regarding CMV in pregnancy.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant women aged 16 years or older with a gestational age of less than 14 weeks.

Not a fit: Patients who are unable to provide informed consent due to language barriers or those with a gestational age above 14 weeks will not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly reduce the incidence of congenital CMV infections and improve child health outcomes.

How similar studies have performed: Other studies have shown promising results with universal CMV screening approaches, indicating potential for success in this pilot program.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* maternal age 16 years or older, and
* gestational age less than 14 weeks.

Exclusion Criteria:

* language barrier preventing informed consent,
* gestational age at blood sampling above 14 weeks, and
* consent withdrawal

Where this trial is running

Badalona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Screeninguniversal screeningpregnancycytomegalovirusvertical transmissionchild health prevention
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.