Understanding why venous tinnitus recurs after surgery
The Recurrence Mechanism of Venous Tinnitus After Boney Wall Reconstruction Based on Multimodal Imaging and Multiphysics Coupling
This study is trying to understand why some people still have venous tinnitus after surgery by looking at how the structure of their bones and blood flow might affect their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Sex | All |
| Sponsor | Beijing Friendship Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing) |
| Trial ID | NCT05856175 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the recurrence of venous tinnitus following bony wall reconstruction surgery. It aims to explore the relationship between the morphology of the peri-sinus bony wall, venous sinus structure, blood flow, and pressure changes that may contribute to the recurrence of this condition. Utilizing advanced multimodal imaging techniques and multiphysics modeling, the study will analyze data from patients to identify key factors influencing postoperative outcomes. The findings could provide insights into improving surgical techniques and patient management.
Who should consider this trial
Good fit: Ideal candidates include patients diagnosed with venous tinnitus who have specific anatomical abnormalities confirmed through imaging.
Not a fit: Patients with contraindications for imaging studies or those with tumors and arterial abnormalities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and management of venous tinnitus, potentially reducing recurrence rates after surgery.
How similar studies have performed: While there is limited data on similar studies, the innovative approach combining multimodal imaging and multiphysics modeling presents a novel exploration of this condition.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients with venous tinnitus, a rhythmic noise that follows the heart beating without external stimuli and can disappear or significantly reduce after compression of the affected side of the neck * the normal otoscopy * venous tinnitus patients with confirmed sigmoid sinus wall dehiscence with or without sigmoid sinuses enlargement, diverticula and transverse sinuses stenosis using dual-phase enhanced CT examination * preoperative DSA examination * bone wall reconstruction Exclusion Criteria: * contraindications for CT and MR Examination * tumor and arterial abnormalities
Where this trial is running
Beijing, Beijing
- Beijing Friendship Hospital, Capital Medical University — Beijing, Beijing, China (Recruiting)
Study contacts
- Principal investigator: Zhenchang Wang, Prof. — Beijing Friendship Hospital
- Study coordinator: Pengfei Zhao, Prof.
- Email: zhaopengf05@163.com
- Phone: +8613811048563
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.