Understanding why thrombolysis fails in heart attack patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify the reasons behind the failure of thrombolytic treatment with tissue-plasminogen activator (t-PA) in patients experiencing acute ST-segment elevation myocardial infarction (STEMI). It will involve 200 STEMI patients who receive prehospital thrombolysis at Oslo University Hospital Ullevål. Blood samples will be collected upon hospital arrival to analyze biomarkers related to coagulation, fibrinolysis, and inflammation. The study will compare these biomarker levels between patients who experience successful and failed thrombolysis to improve risk stratification and treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

STEMI patients \> 18 years given prehospital thrombolysis.

Exclusion Criteria:

None.

Where it's running

• Oslo University Hospital
  Oslo, Norway Recruiting

Study contacts

• Study coordinator: Ragnhild Helseth, MD PhD
• Email: ramhel@ous-hf.no
• Phone: +47 97 14 95 18

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.