Understanding why some people live a very long time in Hong Kong
Official title: Deciphering the Factors of Longevity Through a Multi-Omics Study in Long-Lived Individuals in Hong Kong
Run by Hong Kong University of Science and Technology · NCT07356700 · Data updated 2026-11-12
This study will test whether genetic, environmental, and lifestyle factors help explain why some people stay healthy into extreme old age.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 2500 (estimated) |
| Sponsor | Hong Kong University of Science and Technology Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | February 28, 2031 |
| Study ends | February 28, 2031 |
| Registry record updated | July 8, 2026 |
| Trial ID | NCT07356700 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Han Chinese individuals aged 95 or older who can provide consent and blood samples.
✕Probably not a fit
Individuals who cannot provide consent or refuse blood draws may not benefit from findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This cross-sectional observational study looks at long-lived individuals (95+) in Hong Kong to compare their biology and health data with a younger elderly group (65-94). Researchers will collect demographic, medical, and medication information, blood samples for multi-omics analysis, and cognitive/functional assessments. The goal is to identify factors associated with longevity and healthy aging using an AI-based data approach. The study involves collaboration between HKUST and the Hong Kong Center for Neurodegenerative Diseases and will recruit from community centers and NGOs over five years.
Why it matters
Potential benefit: Findings could help inform strategies to promote healthy aging in the general population.
How similar studies have gone: Previous centenarian studies have identified genetic and biomarker factors linked to longevity; this study builds on that knowledge with a multi-omics and AI approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Han Chinese ethnicity 2. Able to provide official evidence for being 95 years or older (e.g., a birth certificate) 3. Mentally capable of consenting to join the study with or without informant presence 4. Consent to donation of biospecimens (i.e., blood) Exclusion Criteria: 1. Mentally incapable of consenting to join the study even with the presence of an informant 2. Refusal to provide blood samples
Where it's running
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Hong Kong University of Science and Technology
Hong Kong, China Recruiting
Study contacts
- Principal investigator: Nancy Ip, PhD — Hong Kong University of Science and Technology
- Study coordinator: Nancy Ip, PhD
- Email: boip@ust.hk
- Phone: +852-23587304
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.