Understanding vaccine confidence in marginalized communities

Examining Underlying Factors and Root Cause of Successful Evidence Based Interventions (EBIs) Among Historically Marginalized Racial and Ethnic Groups Using the Consolidated Framework for Implementation Research (CFIR)

Boston Medical Center · NCT06639386

This study is trying to understand how confident parents from marginalized communities feel about vaccines for their young children to find ways to encourage more people to get vaccinated.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages18 Years and up
SexAll
SponsorBoston Medical Center (other)
Locations1 site (Boston, Massachusetts)
Trial IDNCT06639386 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore vaccine confidence among historically marginalized racial and ethnic groups, focusing on the MMR and RSV vaccines during pregnancy and early childhood. Researchers will conduct interviews with parents of young children receiving care at Boston Medical Center, as well as with healthcare providers and public health officials. The goal is to identify effective strategies to increase vaccination rates in populations that have historically been vaccine-hesitant. By gathering insights from various stakeholders, the study seeks to address disparities in vaccination outcomes.

Who should consider this trial

Good fit: Ideal candidates include birthing parents of children aged 12-24 months who receive care at Boston Medical Center and are comfortable communicating in English, Spanish, or Haitian Creole.

Not a fit: Patients who are not birthing parents or whose children are outside the specified age range may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved vaccination rates and health outcomes for marginalized populations.

How similar studies have performed: While there have been studies addressing vaccine confidence, this specific focus on marginalized populations and the collaborative approach with various stakeholders is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Parent and child-

* The birthing parent of any age of a child (aged 12-24 months) who receives primary care at Boston Medical Center
* A birthing parent who is registered as a patient at Boston Medical Center
* The birthing parent must have been pregnant between the months of October and February (RSV season)
* The birthing parent must be comfortable completing an interview in English, Spanish, or Haitian Creole.

Clinician

* Clinical provider (including Community Health Workers, Physicians, Physician Assistants and Nurse Practitioners) aged 18+ years at Boston Medical Center within Pediatrics, Family Medicine, or OB/GYN. These clinicians will have been involved in past or current successful vaccine-specific Evidence Based Interventions (EBI) beyond BMC and its affiliated Community Health Center (CHC).

EBI Expert

* Content experts (aged 18+ years) in the areas of Implementation Science, Vaccine-specific EBIs, and Prenatal genetic counseling

Exclusion Criteria:

* Clinical provider (including Community Health Workers, Physicians, Physician Assistants and Nurse Practitioners) at NON-BMC clinic/Community Health Center
* Content experts - NON-Vaccine evidence based interventions (EBIs)

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Vaccine Hesitancy, Vaccine Refusal, Vaccine confidence, Marginalized populations, MMR vaccine, RSV vaccine

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.