Clinical trial No longer in our active list Observational Ages 18 and up

Understanding thirst in ICU patients on mechanical ventilation

Official title: Thirst in the Intensive Care Unit, Recognition, Sensitivity and Type

Run by Assistance Publique - Hôpitaux de Paris · NCT05473351 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study looks at how thirsty patients on breathing machines feel and aims to help doctors better understand and treat this common discomfort in the ICU.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorAssistance Publique - Hôpitaux de Paris
Academic / other
Locations3 sites (Bobigny and 2 other locations)
Trial IDNCT05473351 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who are undergoing invasive mechanical ventilation for at least 24 hours and can communicate their thirst levels.

Probably not a fit

Patients who are unable to communicate verbally, such as those with severe cognitive impairment or delirium, will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the prevalence and intensity of thirst in mechanically ventilated patients who are able to communicate. It will utilize a visual analog scale to measure thirst levels and explore the mechanisms and prognostic implications of this often-overlooked symptom. The study seeks to raise awareness among clinicians about the importance of recognizing and addressing thirst in ICU settings, where patients frequently experience discomfort due to dry mouth and thirst. By focusing on this symptom, the research hopes to improve patient care and outcomes in intensive care units.

Why it matters

Potential benefit: If successful, this study could lead to better recognition and management of thirst in ICU patients, enhancing their comfort and overall care.

How similar studies have gone: While thirst in ICU patients has been noted as a significant issue, this study represents a novel approach to systematically assess and address it.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patient 18 years of age and older
2. Patients undergoing invasive mechanical ventilation for at least 24 hours at one of the participating centers
3. No objection to participation in the study

Exclusion Criteria:

Exclusion Criteria :

1. Patients unable to communicate verbally and reliably self-report thirst:

   * Richmond Agitation-Sedation Scale (RASS) \< -2 or \> +2,
   * delirium according to the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) (if confusion is suspected)
   * severe cognitive impairment or severe mental illness
   * non-French speaking patients
   * severe hearing loss.
2. Pregnant women
3. Adults under legal protection
4. Not affiliated to a social security system or not benefiting from such a system

Where it's running

  • Service de medecine intensive et réanimation, hôpital Pitié Salpêtrière
    Paris, France
    Recruiting
  • Service de médecine intensive et réanimation, hôpital Avicenne
    Bobigny, France
    Not yet recruiting
  • Service de médecine intensive et réanimation, hôpital Saint-Louis
    Paris, France
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.