Understanding thirst in ICU patients on mechanical ventilation
Official title: Thirst in the Intensive Care Unit, Recognition, Sensitivity and Type
Run by Assistance Publique - Hôpitaux de Paris · NCT05473351 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study looks at how thirsty patients on breathing machines feel and aims to help doctors better understand and treat this common discomfort in the ICU.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 3 sites (Bobigny and 2 other locations) |
| Trial ID | NCT05473351 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who are undergoing invasive mechanical ventilation for at least 24 hours and can communicate their thirst levels.
✕Probably not a fit
Patients who are unable to communicate verbally, such as those with severe cognitive impairment or delirium, will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the prevalence and intensity of thirst in mechanically ventilated patients who are able to communicate. It will utilize a visual analog scale to measure thirst levels and explore the mechanisms and prognostic implications of this often-overlooked symptom. The study seeks to raise awareness among clinicians about the importance of recognizing and addressing thirst in ICU settings, where patients frequently experience discomfort due to dry mouth and thirst. By focusing on this symptom, the research hopes to improve patient care and outcomes in intensive care units.
Why it matters
Potential benefit: If successful, this study could lead to better recognition and management of thirst in ICU patients, enhancing their comfort and overall care.
How similar studies have gone: While thirst in ICU patients has been noted as a significant issue, this study represents a novel approach to systematically assess and address it.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patient 18 years of age and older 2. Patients undergoing invasive mechanical ventilation for at least 24 hours at one of the participating centers 3. No objection to participation in the study Exclusion Criteria: Exclusion Criteria : 1. Patients unable to communicate verbally and reliably self-report thirst: * Richmond Agitation-Sedation Scale (RASS) \< -2 or \> +2, * delirium according to the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) (if confusion is suspected) * severe cognitive impairment or severe mental illness * non-French speaking patients * severe hearing loss. 2. Pregnant women 3. Adults under legal protection 4. Not affiliated to a social security system or not benefiting from such a system
Where it's running
-
Service de medecine intensive et réanimation, hôpital Pitié Salpêtrière
Paris, France Recruiting -
Service de médecine intensive et réanimation, hôpital Avicenne
Bobigny, France Not yet recruiting -
Service de médecine intensive et réanimation, hôpital Saint-Louis
Paris, France Not yet recruiting
Study contacts
- Study coordinator: Alexandre DEMOULE, MD, PhD
- Email: alexandre.demoule@aphp.fr
- Phone: 01 42 16 77 61
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.