Understanding the spread and impact of monkeypox in the Democratic Republic of Congo
Monkeypox Biology, Outcome, Transmission and Epidemiology (MBOTE) Study: Epidemiological and Pathophysiological Insights Through a Cross-sectional Survey (EPIC)
This study is trying to understand how monkeypox spreads and affects people in the Democratic Republic of Congo by comparing those who have the virus to those who don’t.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Sex | All |
| Sponsor | Institute of Tropical Medicine, Belgium Academic / other |
| Locations | 2 sites (Kinshasa, Masina and 1 other locations) |
| Trial ID | NCT06840860 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather insights into the epidemiology and pathophysiology of monkeypox (mpox) in the Democratic Republic of Congo (DRC). Researchers will conduct a cross-sectional survey to collect data from patients diagnosed with mpox, analyzing how the virus spreads and affects various demographics. A case-control approach will be employed to compare individuals who test positive for mpox with those who test negative, helping to identify risk factors and assess vaccine effectiveness. The study will take place in regions of the DRC that have experienced significant mpox outbreaks.
Who should consider this trial
Good fit: Ideal candidates for this study include individuals of all ages and sexes who are seeking testing for mpox at designated health centers in the DRC.
Not a fit: Patients under the age of 12 will not benefit from this study due to exclusion from questions regarding sexual health.
Why it matters
Potential benefit: If successful, this study could enhance understanding of monkeypox transmission and improve vaccination strategies, ultimately leading to better patient outcomes.
How similar studies have performed: While this study employs a case-control approach, similar studies have shown success in understanding viral infections and their epidemiology, making this approach promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Apply to be tested for VMPX at HGR or another test center. * Patients of all ages and sexes. However, minors under the age of 12 are excluded from questions on sex life. * The patient or his/her culturally acceptable representative is willing and able to give informed consent for participation in the study. Exclusion Criteria: * NA
Where this trial is running
Kinshasa, Masina and 1 other locations
- Masina Mpox Treatment Center — Kinshasa, Masina, Democratic Republic of the Congo (Not_yet_recruiting)
- Masina Mpox Treatment Center — Kinshasa, Democratic Republic of the Congo (Recruiting)
Study contacts
- Study coordinator: Laurens Liesenborghs, MD, PhD
- Email: lliesenborghs@itg.be
- Phone: 00000000000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.