Understanding the prevalence of severe nausea and vomiting in pregnancy

Hyperemesis Gravidarum Prevalence : A Repeated Cross-sectional Population Based Study

University Hospital, Clermont-Ferrand · NCT06415084

This study is trying to find out how common severe nausea and vomiting is during pregnancy by asking women in Auvergne to fill out online surveys about their experiences.

Quick facts

Study typeObservational
Enrollment604 (estimated)
Ages18 Years to 50 Years
SexFemale
SponsorUniversity Hospital, Clermont-Ferrand (other)
Locations1 site (Clermont-Ferrand)
Trial IDNCT06415084 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the prevalence of hyperemesis gravidarum (HG) among pregnant women in Auvergne. It involves a repeated population-based cross-sectional survey where participants complete online questionnaires to evaluate the severity of nausea and vomiting during their pregnancy. Women will be recruited after their first trimester ultrasound and will be followed up with additional questionnaires in the second and third trimesters. The study seeks to raise awareness about HG and its impact on women's lives.

Who should consider this trial

Good fit: Ideal candidates for this study are French-speaking women with monitored pregnancies in the Auvergne region.

Not a fit: Patients who do not speak French or are incapacitated may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve recognition and management of hyperemesis gravidarum, leading to better support for affected women.

How similar studies have performed: Other studies have highlighted the prevalence and impact of hyperemesis gravidarum, suggesting that this approach is supported by existing literature.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women having a monitored pregnancy in Auvergne,
* Major,
* Speaking French,
* Socially insured,
* Having given their agreement to participate in the study.

Exclusion Criteria:

* Women refusing to participate in the study,
* Not speaking French,
* Major incapacitated persons.

Where this trial is running

Clermont-Ferrand

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Nausea and Vomiting, Nausea vomiting, Pregnancy, Disease prevalence, Hyperemesis gravidarum

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.