Understanding the mechanical properties of human veins

The Mechanical Characterisation of Human Saphenous and Popliteal Vein

University Hospital of Limerick · NCT04016649

This study looks at the strength and flexibility of certain veins that are often thrown away after surgeries to see if they can be used better in future medical treatments.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital of Limerick (other)
Locations1 site (Limerick, Limerick)
Trial IDNCT04016649 on ClinicalTrials.gov

What this trial studies

This observational study aims to characterize the mechanical properties of human saphenous and popliteal veins that are typically discarded after varicose vein procedures, lower limb amputations, and bypass surgeries. By analyzing the stress-stretch relationship of these vein segments, the study seeks to enhance the understanding of treatment techniques and improve the design of mechanical devices. The findings could also help assess the suitability of these veins as conduits for bypass and arteriovenous fistula procedures.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older undergoing varicose vein procedures, lower limb amputations, or bypass surgeries.

Not a fit: Patients who are unable to provide informed consent or are seriously ill may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical techniques and better outcomes for patients requiring vascular interventions.

How similar studies have performed: While this approach is focused on mechanical characterization, similar studies have shown promise in improving vascular treatment techniques.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or Female patients aged 18 years or older
* Patients undergoing varicose vein procedures or;
* Patients undergoing lower limb amputation or;
* Patients undergoing lower limb bypass surgery

Exclusion Criteria:

* Patients unable to give informed consent
* Seriously ill/unconscious patients

Where this trial is running

Limerick, Limerick

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Peripheral Vascular Diseases

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.