Understanding the long-term effects of COVID-19 on veterans with chronic lung disease
Chronic Lung Disease and COVID-19: Understanding Severity, Recovery and Rehabilitation Needs (LAUREL Study)
This study looks at how COVID-19 affects veterans with chronic lung diseases over time to see how they recover and what help they might need.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 476 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | VA Office of Research and Development Federal |
| Locations | 2 sites (Ann Arbor, Michigan and 1 other locations) |
| Trial ID | NCT04628039 on ClinicalTrials.gov |
What this trial studies
This study investigates the long-term consequences of COVID-19, particularly in veterans with chronic lung diseases. It employs a retrospective cohort approach to analyze factors associated with COVID-19 severity and complications, as well as a mixed-methods prospective cohort study that includes surveys and interviews with patients and their caregivers. The aim is to assess health recovery, functional outcomes, and rehabilitation needs following COVID-19 infection. The study will also explore the impact of social determinants of health on recovery and severity.
Who should consider this trial
Good fit: Ideal candidates include VA patients diagnosed with COVID-19 and their caregivers, as well as patients with lower respiratory tract infections who tested negative for COVID-19.
Not a fit: Patients with cognitive limitations that prevent communication or those facing language barriers may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the rehabilitation needs and long-term care strategies for veterans recovering from COVID-19.
How similar studies have performed: Other studies have shown success in understanding the long-term effects of COVID-19, particularly in specific populations, making this approach both relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * (Patients in COVID-19 cohort) VA patients diagnosed with COVID-19 through a positive PCR (Polymerase Chain Reaction) or antigen SARS-CoV-2 test conducted in VA * (Caregivers) Providing caregiving to VA patients diagnosed with COVID-19 * (Patients in LRTI cohort) VA patients diagnosed with LRTI and tested negative for COVID-19 (through PCR and/or antigen test) Exclusion Criteria: * Cognitive limitations that preclude the ability to communicate and obtain informed consent * Language barriers
Where this trial is running
Ann Arbor, Michigan and 1 other locations
- VA Ann Arbor Healthcare System, Ann Arbor, MI — Ann Arbor, Michigan, United States (Recruiting)
- VA Puget Sound Health Care System Seattle Division, Seattle, WA — Seattle, Washington, United States (Recruiting)
Study contacts
- Principal investigator: Kristina A Crothers, MD — VA Puget Sound Health Care System Seattle Division, Seattle, WA
- Study coordinator: John R Kundzins, BS
- Email: John.Kundzins@va.gov
- Phone: (206) 277-1515
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.