Understanding the impact of smoking and drinking on cancer treatment outcomes
Assessment of Tobacco Smoking and Alcohol Drinking and Treatment Outcomes Among Patients With Lung or Head and Neck Cancer
This study looks at how smoking and drinking habits affect the treatment results for adults newly diagnosed with lung or head and neck cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 165 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 4 sites (Bron and 3 other locations) |
| Trial ID | NCT05523583 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather information on how tobacco smoking and alcohol consumption affect treatment outcomes in patients newly diagnosed with lung or head and neck cancer. It will involve a longitudinal cohort of adult patients who will be recruited at the time of their diagnosis. Participants will complete questionnaires to provide insights into their smoking and drinking habits, which will help inform cessation support strategies in their cancer care. The study is conducted at the Hospices Civils de Lyon, focusing on patients undergoing front-line treatment.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have been newly diagnosed with lung or head and neck cancer and have smoked at least once in the past 30 days.
Not a fit: Patients with a history of another lung or head and neck cancer within the past five years or those unable to participate for psychosocial reasons may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved cessation support for cancer patients, potentially enhancing their treatment outcomes.
How similar studies have performed: Other studies have shown that addressing smoking and alcohol use can positively impact cancer treatment outcomes, suggesting this approach may be beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients newly diagnosed with lung cancer or head \& neck cancer (International Classification of Diseases 10: C76, C34) * Patients who undergo front-line treatment * Age 18 years or older * Benefiting from a Social Security scheme * Written information about the study provided to the patient before any procedure specific to the study * Patients who had at least one episode of smoking within the past 30 days before diagnosis Exclusion Criteria: * History of another lung or head \& neck cancer \< 5 years (Note: The presence of a second tumour location, discovered at the same time as the lung or head and neck cancer, does not constitute a non-inclusion criterion) * History of another cancer (except for curatively treated cervical cancer in situ and non-melanoma skin cancer) \< 3 years * Mesothelioma, thymic malignancies, and cancer of the upper oesophagus * Inability to complete the study for psychosocial reasons (inability to schedule interview (homeless), no access to phone, psychological disorder leading to inability to answer phone interview, do not speak French and no easy access to translator from surroundings) * Patient under guardianship * Patient refusal
Where this trial is running
Bron and 3 other locations
- Hôpital Louis Pradel, Pneumologie — Bron, France (Recruiting)
- Hôpital de la Croix-Rousse, Oto-Rhino-Laryngologie et Chirurgie Cervico-Faciale — Lyon, France (Recruiting)
- Hôpital de la Croix-Rousse, Pneumologie — Lyon, France (Recruiting)
- Hôpital Lyon Sud, Pneumologie — Pierre-Bénite, France (Recruiting)
Study contacts
- Study coordinator: Sébastien COURAUD, MD
- Email: sebastien.couraud@chu-lyon.fr
- Phone: 478864401
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.