Understanding the HeartMate 3 device and its impact on patients
Official title: Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
Run by International Consortium of Circulatory Assist Clinicians · NCT06039176 · Data updated 2026-11-12
This study looks at how the HeartMate 3 device affects patients with advanced heart failure by checking for problems like bleeding and infection, while also seeing how it impacts their quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | International Consortium of Circulatory Assist Clinicians Academic / other |
| Locations | 7 sites (San Francisco, California and 6 other locations) |
| Status | Recruiting |
| Started | October 27, 2023 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | December 16, 2025 |
| Trial ID | NCT06039176 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who are scheduled for implantation of a HeartMate 3 dLVAD.
✕Probably not a fit
Patients under 18 years of age or those scheduled for a dLVAD that is not a HeartMate 3 device may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the relationship between data from the HeartMate 3 left ventricular assist device (dLVAD) and clinical outcomes in patients with advanced heart failure. It focuses on understanding the prevalence of adverse events such as bleeding, infection, and stroke in patients receiving this device, as well as how the device's data correlates with patients' quality of life post-implantation. By analyzing pump data and clinical practices, the study seeks to improve predictions of complications and enhance patient management strategies.
Why it matters
Potential benefit: If successful, this study could lead to better prediction and management of complications for patients with advanced heart failure receiving a dLVAD.
How similar studies have gone: While there have been studies on other dLVADs, this specific approach focusing on the HeartMate 3 device and its data correlation with clinical outcomes is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older * Scheduled Heartmate 3 ® dLVAD implantation Exclusion Criteria: * \<18 years of age * Scheduled for dLVAD that is NOT a Heartmate 3 (R) device
Where it's running
-
UCSF
San Francisco, California, United States Recruiting -
University of Florida
Gainesville, Florida, United States Recruiting -
University of Chicago
Chicago, Illinois, United States Recruiting -
Mayo Clinic-Rochester
Rochester, Minnesota, United States Recruiting -
University of Kansas Medical Center
Kansas City, Kansas, United States Active not recruiting -
Musc
Charleston, South Carolina, United States Active not recruiting
Show 1 more location
-
University of Utah
Salt Lake City, Utah, United States Active not recruiting
Study contacts
- Principal investigator: Sarah E Schroeder, PhD MSN RN — International Consortium of Circulatory Assist Clinicians
- Study coordinator: Sarah E Schroeder, PhD MSN RN
- Email: sarah.schroeder@vadcoordinator.org
- Phone: 402-937-3595
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Rural Telemedicine-Enabled Care to Prevent Stroke in Older Adults in China
A telemedicine-supported care model led by rural doctors will be tested to see if it can reduce stroke and heart problems in adults 65+ living in rural China.
-
Catheter ablation plus LAAC vs anticoagulation in frail elderly A-fib patients
This study tests whether adding left atrial appendage closure to ablation is as good as using long-term blood thinners in frail people aged 75 and up with atrial fibrillation.
-
Taining Golden Lake comprehensive chronic disease management program
This project will build a large cohort of adults in Taining County to collect health data and try to create a county-level chronic disease management model for people with hypertension, diabetes, dyslipidemia, and other long-term conditions.
-
Managing multiple medications in older adults with chronic diseases
This project will see if taking many different medicines changes the health outlook of people aged 65 and older who have chronic conditions.
-
Lowering blood pressure after stroke with home monitoring and virtual group visits
This will see if adding virtual group visits to home blood pressure checks helps lower blood pressure in people who had a recent mild-to-moderate stroke.
-
Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.