Understanding the genetic causes of moles

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to investigate the genetic mutations associated with melanocytic nevi, commonly known as moles. Researchers will collect DNA from skin biopsy specimens of nevi and corresponding blood samples to perform whole genome, whole exome, or targeted sequencing. The goal is to identify somatic mutations in the nevi by comparing them to normal tissue DNA. This observational approach will help clarify the genetic basis of these benign skin lesions.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Male or female subjects that are 18 years or older
* Subjects with melanocytic nevi\\

Exclusion criteria:

* Patients less than 18 years of age
* Patients without melanocytic nevi
* Patients with a bleeding disorder or are taking anticoagulation medication

Where it's running

• University of California-Davis, Department of Dermatology
  Sacramento, California, United States Recruiting

Study contacts

• Study coordinator: Maija Kiuru, MD
• Email: mkiuru@ucdavis.edu
• Phone: 916-734-0591

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• AI tool helps dermatologists decide if a skin lesion could be melanoma

  A computer tool called DEXI tested with DermaGraphix Visualizer helps dermatologists see if a skin lesion might be melanoma and aims to reduce unnecessary biopsies.

  Recruiting at 7 sites Phase 3 Memorial Sloan Kettering Cancer Center · Stanford, California and 7 other locations · NCT07890415

• Confocal imaging and genetic testing of atypical moles and early melanoma

  This project will try to see if noninvasive confocal images of suspicious moles match genetic changes from sequencing in adults who are having the lesions removed.

  Recruiting University of Modena and Reggio Emilia · Modena, Mo · NCT07277920

• Optimizing Adaptive Deep Brain Stimulation for Parkinson's Disease

  This study tests whether using ongoing brain signals gathered during daily life can improve adaptive deep brain stimulation for people with Parkinson's who have motor fluctuations.

  Recruiting University of California, Davis · Davis, California · NCT07798271

• How movement and nervous system function relate after stroke

  This study tests whether measures of movement efficiency and nerve function relate to outcomes in adults who had a stroke.

  Recruiting University of California, Davis · Sacramento, California · NCT07737873

• Support for caregivers of people with heart disease to reduce stress

  This study tests whether the Confident Caregiver program can help family caregivers of people with cardiovascular disease feel less burdened and stressed, with sessions delivered virtually.

  Recruiting University of California, Davis · Sacramento, California · NCT07717723

• Normal lymphatic anatomy in breast cancer patients using ultra-high frequency ultrasound and ICG

  This study tests whether ultra-high frequency ultrasound plus indocyanine green dye can map normal lymphatic channels in breast cancer patients undergoing axillary procedures.

  Recruiting University of California, Davis · Sacramento, California · NCT07677839

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.