Understanding the features of Restless Legs Syndrome.

Clinical Features Associated With Restless Legs Syndrome : Clin-RLS

Observational University Hospital, Montpellier · NCT05044520

This study looks at how different factors like symptoms, other health conditions, and medications affect people with Restless Legs Syndrome over time.

Quick facts

Study typeObservational
Enrollment2000 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Montpellier Academic / other
Locations1 site (Montpellier)
Trial IDNCT05044520 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the evolution of symptoms in patients with Restless Legs Syndrome (RLS) by examining clinical, biological, and pharmacological factors. It will involve a large cohort of RLS patients who are members of the French RLS association and other European RLS associations. The study will focus on how RLS phenotype, comorbidities, and medications influence the severity of symptoms over time. By gathering data from this population, the study seeks to provide insights into the natural course of RLS and its complications.

Who should consider this trial

Good fit: Ideal candidates for this study are French-speaking adults diagnosed with Restless Legs Syndrome who are members of the RLS association.

Not a fit: Patients who are not members of the RLS association or those who are legally protected or deprived of liberty may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of Restless Legs Syndrome, enhancing patient quality of life.

How similar studies have performed: While there have been few studies on RLS, this study's comprehensive approach to understanding symptom evolution is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* Adults subjects
* Restless legs syndrome diagnosis
* Member of the restless legs syndrome association
* French speaking
* Able to understand the study
* Signed written informed consent
* Affiliated to social security

Exclusion criteria:

\- Vulnerable subject : subject deprived of liberty or protected by law (trusteeship, legal guardianship)

Where this trial is running

Montpellier

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Restless Legs SyndromeRestless legs syndromeAugmentation syndromeDopamine agonistsAlpha 2 delta ligandsOpiates
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.