Understanding the evolution of cervical paragangliomas

Prognostic's Factors of Head and Neck Paragangliomas Evolution

Hospices Civils de Lyon · NCT05233878

This study looks at adults with rare neck tumors called cervical paragangliomas to see how they develop and what factors might affect their treatment and outcomes.

Quick facts

Study typeObservational
Enrollment25 (estimated)
Ages18 Years and up
SexAll
SponsorHospices Civils de Lyon (other)
Locations1 site (Bron)
Trial IDNCT05233878 on ClinicalTrials.gov

What this trial studies

This observational study aims to characterize a population of patients diagnosed with cervical paragangliomas, which are rare tumors arising from chromaffin tissue in the neck. The study will include individuals aged 18 and over who have a confirmed diagnosis of one or multiple cervical paragangliomas without prior specific therapy. By examining the clinical and radiological characteristics of these tumors, the study seeks to identify prognostic factors that may influence their evolution and treatment outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and over with a confirmed diagnosis of cervical paragangliomas who have not received any specific therapy.

Not a fit: Patients who have already undergone treatment for paragangliomas or have a life expectancy of less than 2 years may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the management and treatment of cervical paragangliomas, potentially improving patient outcomes.

How similar studies have performed: While there is limited data on similar studies, the characterization of rare tumors like cervical paragangliomas is crucial for understanding their behavior and improving treatment strategies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Man or woman aged 18 or over
* Patient with a confirmed diagnosis of one or multiple cervical paragangliomas regardless of genetic predisposition without specific therapy
* Patient informed of the study details and who didn't opposed to participate in this research

Exclusion Criteria:

* Patient already treated without initial clinical and radiologic assessment standardized
* Patient already treated with surgery, radiotherapy or systemic therapy for another paraganglioma
* Patient with evolutive disease and life expectancy less than 2 years
* Patient placed under legal protection
* Patient participating in another interventional clinical study that may interfere with the results of this study

Where this trial is running

Bron

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Paraganglioma, Cervical paragangliomas

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.