Understanding the effects of 3q29 deletion and duplication syndromes
Official title: The 3q29 Deletion and 3q29 Duplication: Architecture of Behavioral Phenotypes
Run by Rutgers, The State University of New Jersey · NCT02447861 · Data updated 2026-11-12
This study is trying to learn more about the health and behavior effects of 3q29 deletion and duplication syndromes in people who have these conditions, their healthy siblings, and others of similar age.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 800 (estimated) |
| Sponsor | Rutgers, The State University of New Jersey Academic / other |
| Locations | 1 site (Piscataway, New Jersey) |
| Status | Recruiting |
| Started | July 2013 |
| Main results expected | January 2028 |
| Study ends | January 2028 |
| Registry record updated | May 20, 2026 |
| Trial ID | NCT02447861 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with 3q29 deletion or duplication syndromes, their healthy siblings, or age-matched controls.
✕Probably not a fit
Patients with clinically significant medical diseases that would prevent participation in the study procedures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the medical and behavioral consequences of 3q29 deletion and duplication syndromes, which are caused by genetic abnormalities on chromosome 3. Participants include individuals diagnosed with either syndrome, their healthy siblings, or age-matched controls. The study seeks to gather comprehensive data to better understand the phenotypes associated with these genetic conditions. By analyzing the behaviors and health outcomes of affected individuals, researchers hope to provide insights into the impact of these syndromes.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management strategies for individuals with 3q29 deletion and duplication syndromes.
How similar studies have gone: While this study focuses on specific genetic syndromes, similar observational studies have successfully provided insights into other genetic conditions, suggesting potential for valuable findings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of 3q29 deletion or 3q29 duplication * Consent from parents or guardians or an adult with 3q29 deletion or 3q29 duplication that does not require a legal guardian or an adult who is the healthy sibling of an individual with 3q29 deletion or 3q29 duplication or a healthy age-matched control Exclusion Criteria: * Clinically significant medical disease that would prohibit participation in the study procedures
Where it's running
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Internet-Based
Piscataway, New Jersey, United States Recruiting
Study contacts
- Principal investigator: Jennifer Mulle, MHS, PhD — Rutgers University
- Study coordinator: Jennifer G Mulle, MHS, PhD
- Email: jennifer.mulle@rutgers.edu
- Phone: (848) 445-9866
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.