Understanding the effects of 3q29 deletion and duplication syndromes
The 3q29 Deletion and 3q29 Duplication: Architecture of Behavioral Phenotypes
This study is trying to learn more about the health and behavior effects of 3q29 deletion and duplication syndromes in people who have these conditions, their healthy siblings, and others of similar age.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 800 (estimated) |
| Sex | All |
| Sponsor | Rutgers, The State University of New Jersey Academic / other |
| Locations | 1 site (Piscataway, New Jersey) |
| Trial ID | NCT02447861 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the medical and behavioral consequences of 3q29 deletion and duplication syndromes, which are caused by genetic abnormalities on chromosome 3. Participants include individuals diagnosed with either syndrome, their healthy siblings, or age-matched controls. The study seeks to gather comprehensive data to better understand the phenotypes associated with these genetic conditions. By analyzing the behaviors and health outcomes of affected individuals, researchers hope to provide insights into the impact of these syndromes.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with 3q29 deletion or duplication syndromes, their healthy siblings, or age-matched controls.
Not a fit: Patients with clinically significant medical diseases that would prevent participation in the study procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management strategies for individuals with 3q29 deletion and duplication syndromes.
How similar studies have performed: While this study focuses on specific genetic syndromes, similar observational studies have successfully provided insights into other genetic conditions, suggesting potential for valuable findings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of 3q29 deletion or 3q29 duplication * Consent from parents or guardians or an adult with 3q29 deletion or 3q29 duplication that does not require a legal guardian or an adult who is the healthy sibling of an individual with 3q29 deletion or 3q29 duplication or a healthy age-matched control Exclusion Criteria: * Clinically significant medical disease that would prohibit participation in the study procedures
Where this trial is running
Piscataway, New Jersey
- Internet-Based — Piscataway, New Jersey, United States (Recruiting)
Study contacts
- Principal investigator: Jennifer Mulle, MHS, PhD — Rutgers University
- Study coordinator: Jennifer G Mulle, MHS, PhD
- Email: jennifer.mulle@rutgers.edu
- Phone: (848) 445-9866
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.