Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Understanding the costs of self-control

Official title: Neural and Affective Mechanisms Underlying Prospective Self-control Costs

Run by NYU Langone Health · NCT05795179 · Data updated 2026-11-12

This study is trying to see how much people are willing to pay to resist tempting rewards that can lead to self-control problems, while also looking at how stress affects their decision-making.

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment300 (estimated)
SponsorNYU Langone Health
Academic / other
Locations1 site (New York, New York)
StatusRecruiting
StartedOctober 1, 2024
Main results expectedDecember 1, 2027
Study endsApril 1, 2028
Registry record updatedMarch 11, 2026
Trial IDNCT05795179 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-70 who are fluent in English and are actively maintaining or losing weight through dietary changes.

Probably not a fit

Patients with a history of neurological or psychiatric diseases, certain medical conditions, or those who are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the cognitive, neural, and affective mechanisms behind self-control failures, which are common challenges for many individuals. Participants will engage in a decision-making task to assess how much they are willing to pay to avoid tempting rewards that could lead to self-control issues. The study will utilize various stress-inducing tasks and functional magnetic resonance imaging (fMRI) to explore the neural correlates and connectivity patterns associated with self-control costs. By examining the impact of different stressors, the research aims to deepen our understanding of the factors influencing self-control.

Why it matters

Potential benefit: If successful, this study could provide insights into the mechanisms of self-control, potentially leading to better strategies for managing self-control failures.

How similar studies have gone: While the specific approach of this study may be novel, previous research has explored related concepts of self-control and stress, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18-70 years of age, able to speak, read, and write fluently in English
* be willing and able to follow study procedures and provide informed consent.
* Must additionally confirm they are on a diet to maintain/lose weight and are implementing/maintaining dietary changes.

Exclusion Criteria:

* History of or medication for neurologic or psychiatric disease
* High-blood pressure or heart condition
* Diabetes, food allergies, metabolic disorders or history of eating disorder
* Use of corticosteroids or beta-blockers
* Metallic implants or devices contraindicating magnetic resonance imaging.
* Pregnancy is considered an exclusion criteria due to all stress and scanning procedures, thus pregnant participants will not be permitted to participate in the study.

Where it's running

  • NYU Langone Health
    New York, New York, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.