Understanding the coronary circulation in Takotsubo syndrome
Official title: Characterisation of the Biochemical Profile and Physiology of the Coronary Circulation in Takotsubo Syndrome
Run by A.O.U. Città della Salute e della Scienza · NCT06669962 · Data updated 2026-11-12
This study looks at how blood flow in the tiny heart vessels works in people with Takotsubo syndrome to see how it affects their symptoms and recovery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | A.O.U. Città della Salute e della Scienza Academic / other |
| Locations | 1 site (Turin, Turin) |
| Status | Recruiting |
| Started | July 10, 2024 |
| Main results expected | June 27, 2026 |
| Study ends | June 27, 2027 |
| Registry record updated | November 1, 2024 |
| Trial ID | NCT06669962 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older diagnosed with Takotsubo syndrome.
✕Probably not a fit
Patients under 18 years old or those who refuse to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study includes consenting patients over 18 years old diagnosed with Takotsubo syndrome to evaluate the incidence of coronary microcirculation dysfunction. It aims to correlate this dysfunction with clinical presentations and prognosis. Secondary endpoints include assessing in-hospital mortality, cardiogenic shock prevalence, and the relationship between biomarkers and microvascular dysfunction. The study will follow patients for one month and one year after enrollment, which lasts for two years.
Why it matters
Potential benefit: If successful, this study could improve the understanding and management of Takotsubo syndrome, potentially leading to better patient outcomes.
How similar studies have gone: While there have been studies on Takotsubo syndrome, this specific focus on coronary microcirculation dysfunction is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years; * Diagnosis of Takotsubo syndrome * Signing of informed consent Exclusion Criteria: * Age \<18 years; * Refusal to sign written informed consent.
Where it's running
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AOU Città della Salute e della Scienza
Turin, Turin, Italy Recruiting
Study contacts
- Study coordinator: Ovidio De Filippo, MD
- Email: odefilippo@cittadellasalute.to.it
- Phone: +390116336023
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Registry of patients with Takotsubo syndrome
This study is creating a national registry to track and learn more about patients with Takotsubo syndrome, also known as broken heart syndrome, by following their health and quality of life over time.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.