Understanding the causes of sarcopenic obesity in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the molecular and cellular mechanisms behind sarcopenic obesity, a condition affecting the elderly characterized by the coexistence of obesity and reduced muscle mass. By evaluating patients who are candidates for hip surgery and healthy older adults, the study seeks to uncover how increased fat mass and decreased muscle tissue contribute to this growing public health issue. The research will focus on the interplay between chronic inflammation, hormonal changes, and metabolic alterations in skeletal muscle. Through clinical evaluations, the study hopes to provide insights into the pathophysiology of sarcopenic obesity.

Why it matters

Who can join: the full rules

Inclusion Criteria:

patients who are candidates for hip surgery

* patients who are candidates for hip surgery
* age ≥ 65 years
* patients able to give consent

healthy subjects

\- healthy subjects from the geriatric cohort studied in 2016-2017 who at that time were: were overweight (25 ≤ BMI \< 30 kg/m2) or obese (BMI ≥ 30 kg/m2) but had not yet developed sarcopenia

Exclusion Criteria:

All partecipants

* unavailability to participate in the study
* inflammatory or neurological myopathies
* acute heart failure
* active cancer

Where it's running

• Ospedale San Raffaele
  Milan, Italy Recruiting

Study contacts

• Study coordinator: Patrizia Rovere Querini, PhD, MD
• Email: rovere.patrizia@hsr.it
• Phone: +390226436095

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Understanding Sarcopenic Obesity in COPD Patients

  This study is trying to see how common sarcopenic obesity is in people with COPD and how it affects their breathing, disease severity, and quality of life.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.