Understanding sensory and motor functions of the posterior parietal cortex
Sensori-motor and Perceptual Functions of the Posterior Parietal Cortex (PPC) in Patients With Optic Ataxia (AO) and Healthy Subjects.
This study is testing how problems in a part of the brain affect the ability of people with optic ataxia to coordinate their hand movements and perceive their surroundings compared to healthy individuals.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 160 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Bron) |
| Trial ID | NCT03286686 on ClinicalTrials.gov |
What this trial studies
This study investigates how the posterior parietal cortex (PPC) integrates sensory information to guide hand movements towards targets. It compares the sensory motor and perceptual performance of patients with optic ataxia, a condition caused by PPC lesions, to that of healthy volunteers. The research employs six behavioral tests to assess the impact of PPC impairment on visual-motor coordination and perception. The goal is to objectify how these impairments affect patients' quality of life and autonomy.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 18 to 75 with neurological injuries in the posterior parietal cortex and symptoms of optic ataxia.
Not a fit: Patients with other neurological, psychiatric, sensory, or motor troubles that prevent task compliance may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of optic ataxia and improve rehabilitation strategies for affected patients.
How similar studies have performed: While studies on sensory integration and motor planning exist, this specific focus on optic ataxia and PPC functions is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: All patients and healthy subjects: * male and female, age from 18 to 75 years included * normal vision or corrected vision * covered by social security * signed written informed consent Patients: * neurological injury in posterior parietal cortex supported by a cerebral MRI * present optic ataxia symptoms Healthy subjects * no known neurological injury Exclusion Criteria: \- unable to comply with the tasks (neurological, psychiatric, sensory or motor troubles)
Where this trial is running
Bron
- U1028 INSERM - CNRS UMR 5292 Equipe ImpAct — Bron, France (Recruiting)
Study contacts
- Principal investigator: Laure PISELLA, PhD — INSERM U1028 - Impact - CRNL
- Study coordinator: Laure PISELLA, PhD
- Email: laure.pisella@inserm.fr
- Phone: 4 72 91 34 05
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.