Understanding recurrence patterns in head and neck cancer

Identification of Pattern and Factors Affecting Recurrence of Head and Neck Carcinoma After Radical IMRT and VMAT

Observational Sohag University · NCT06465030

This study looks at how and where head and neck cancer comes back in patients treated with advanced radiation methods to see if there are any patterns that can help improve treatment outcomes.

Quick facts

Study typeObservational
Enrollment35 (estimated)
Ages18 Years and up
SexAll
SponsorSohag University Academic / other
Locations1 site (Sohag)
Trial IDNCT06465030 on ClinicalTrials.gov

What this trial studies

This observational study aims to analyze the local experiences in treating head and neck squamous cell carcinoma (SCC) by retrospectively examining the incidence and locations of cancer recurrence. The research will focus on local, regional, and distant metastases in patients treated with advanced radiation techniques such as IMRT and VMAT from 2018 to 2022. By evaluating these factors, the study seeks to identify patterns and influences on recurrence, providing insights into treatment outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 with primary non-nasopharyngeal head and neck squamous cell carcinoma who received radical treatment using IMRT and VMAT.

Not a fit: Patients with double malignancies or metastatic head and neck squamous cell carcinoma may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of recurrence in head and neck cancer, potentially leading to improved treatment strategies.

How similar studies have performed: While this study focuses on local experiences, similar observational studies have shown success in identifying recurrence patterns in other cancer types, suggesting potential for valuable insights here.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged more than 18 years. Patients with primary non nasopharyngeal head and neck squamous cell carcinoma. Patients who were intended to receive radical treatment delivered by IMRT and VMAT techniques.

Exclusion Criteria:

* Adults who had double malignancies. Metastatic HNSCC cases.

Where this trial is running

Sohag

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Recurrent Head and Neck Squamous Cell Carcinoma
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.