Understanding recovery in patients with cervical radiculopathy after surgery
Functioning in Individuals with Cervical Radiculopathy After Posterior Cervical Decompression: a Prospective Multicenter Observational Study with a 2 Year Follow-up.
This study is looking at how well people recover from surgery for neck pain caused by nerve issues, focusing on their pain, function, and quality of life over two years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 154 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Linkoeping University Government |
| Locations | 3 sites (Jönköping and 2 other locations) |
| Trial ID | NCT05310578 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the pain, function, psychosocial factors, and health-related quality of life in individuals with cervical radiculopathy following posterior cervical decompression surgery. It will involve a prospective multicenter longitudinal cohort of 154 patients who will undergo cervical foraminotomy with or without laminectomy. Participants will be followed up at three, 12, and 24 months postoperatively to assess their neck-specific function and overall recovery. The study seeks to fill the knowledge gap regarding postoperative outcomes in this patient population.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-75 with confirmed cervical radiculopathy and persistent arm pain for at least three months, scheduled for posterior cervical decompression.
Not a fit: Patients with moderate to high myelopathy, previous cervical spine surgeries, or severe mental disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into recovery patterns and improve postoperative care for patients with cervical radiculopathy.
How similar studies have performed: While similar studies have explored postoperative outcomes in cervical radiculopathy, this specific observational approach focusing on a multicenter cohort is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Cervical radiculopathy, confirmed by MRI images (or alternative neuroradiological imaging if MRI contraindicated) compatible with clinical findings of nerve root compression (neurological examination performed by a neurosurgeon/orthopedic surgeon) * Posterior cervical decompression as foraminotomy with our without laminectomy * At least 3 months of persistent arm pain * Age 18-75 years Exclusion Criteria: * Nurick score 2 or more (to exclude individuals with moderate to high myelopathy) * Previous surgery of cervical spine * Previous fracture or dislocation of the cervical spine * Malignancy or benign spinal tumor (eg, neuromas) * Spinal infection * Previous spondylodiscitis * Servere mental disorder * Known alcohol or drug abuse * Lack of ability to write/comprehend/express oneself in Swedish
Where this trial is running
Jönköping and 2 other locations
- Neuro-ortopediska kliniken — Jönköping, Sweden (Recruiting)
- Neurosurgery clinic — Linköping, Sweden (Recruiting)
- Ryggkirurgiskt Centrum — Stockholm, Sweden (Recruiting)
Study contacts
- Principal investigator: Anneli Peolsson, PhD — Linköping University, Department of Health, Medicine and Caring Sciences, Unit of physiotherapy
- Study coordinator: Jard Svensson, MSc
- Email: jard.svensson@liu.se
- Phone: +46101034026
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.