Clinical trial Recruiting at 1 site Observational Ages 18 to 85

Understanding recovery after stroke

Official title: Learning the Natural History of Recovery After Stroke - Cognitive, Motor and Sensory Function

Run by Adi Negev-Nahalat Eran · NCT06441552 · Data updated 2026-11-12

This study is tracking how people recover after a stroke by looking at their thinking, movement, and feeling abilities over time to see how different rehab programs can help them feel better.

Quick facts

Study typeObservational
Ages18 Years to 85 Years
SexAll
Enrollment200 (estimated)
SponsorAdi Negev-Nahalat Eran
Academic / other
Locations3 sites (Haifa and 2 other locations)
StatusRecruiting
StartedFebruary 1, 2024
Main results expectedJanuary 2027
Study endsJanuary 2027
Registry record updatedOctober 3, 2025
Trial IDNCT06441552 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults over 18 who were independent in daily activities before their first or recurrent stroke and are currently medically stable.

Probably not a fit

Patients with degenerative neurological conditions, significant psychiatric issues, or severe orthopedic conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This longitudinal observational study aims to track the recovery process following a stroke by monitoring changes in cognitive, motor, and sensory functions over time. It is part of the RESTRO project, which evaluates a neurorehabilitation program designed to enhance recovery and quality of life for stroke patients. Data will be collected from three primary sites over a period of 6 to 12 months, allowing researchers to analyze the relationship between rehabilitation intensity and patient outcomes.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into effective rehabilitation strategies that enhance recovery after stroke.

How similar studies have gone: Other studies focusing on stroke recovery and rehabilitation have shown promising results, indicating that this approach is grounded in existing research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \>18 years of age
* Independent in all activities of daily living before the stroke.
* In- and out-patients at Adi-Negev Nahalat-Eran rehabilitation center, with first ever stroke, or with a recurrent stroke that did not lead to disability (were independent in ADL before the second stroke).
* Medically stable
* Able to provide informed consent.

Exclusion Criteria:

* The presence of any degenerative neurological condition, neuropathy, myopathy or Polio that are not secondary to stroke, excluding diabetic related changes.
* Traumatic brain injury and/or extra-cerebral hemorrhage.
* Significant psychiatric condition, including alcoholism and drug abuse.
* Any severe orthopedic condition (such as amputation or severe pain that limits activity) or chronic pain syndrome.
* Participation in another interventional study.

Where it's running

  • Adi-Negev Nahalat Eran
    Ofakim, Israel
    Recruiting
  • Rambam/Technion
    Haifa, Israel
    Not yet recruiting
  • Al-Ahli hospital
    Hebron, Palestinian Territories
    Not yet recruiting

Study contacts

  • Principal investigator: Simona Bar-Haim, PhD — Ben-Gurion University of the Negev
  • Study coordinator: Simona Bar-Haim, PhD
  • Email: barhaims@bgu.ac.il
  • Phone: 972-54-470-2553

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Self-Supervised Constraint-Induced Movement Therapy for Stroke Recovery

    This study tests a partly self-guided therapy program to help adults recover the use of their weaker arm after stroke, aiming to require less time with a therapist.

    Recruiting Ohio State University · Columbus, Ohio · NCT07723300

  • CHORDS Cerebral Protection During TAVR

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    Recruiting at 14 sites Resonova (Shanghai) Medtech Limited · Bengbu, Anhui and 14 other locations · NCT07648693

  • Comparing different pressure garments for improving upper limb function after stroke

    This study is testing which type of pressure garment can help stroke patients improve their arm function and quality of life over eight weeks.

    Recruiting at 3 sites National University of Malaysia · Weifang, Shandong and 2 other locations · NCT06587308

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.