Understanding postoperative delirium in elderly patients after non-cardiac surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the incidence of postoperative delirium (POD) in elderly patients aged over 65 undergoing elective non-cardiac surgeries. It will involve 150 patients classified as ASA Physical Status I-III and will utilize the validated 4 A's test for rapid assessment of delirium. The study will explore various predisposing and precipitating factors contributing to POD, with a focus on improving patient outcomes and reducing healthcare costs associated with this complication. The findings could help in identifying at-risk patients and implementing preventive strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients of age \>65yrs
* Either sex
* ASA physical status I - III
* Elective non-cardiac surgical procedures under general anesthesia
* Clinical Frailty Score (CFS): 1-8
* Patients requiring at least 24 hours of postoperative inpatient care.

Exclusion Criteria:

* Clinical Frailty Score (CFS) of 9
* Patients diagnosed with dementia, severe psychiatric or neurological diseases
* Recent surgery within past 3-months
* History of recent head injury in the preceding 3 months
* Patients with uncompensated cardiovascular disease, hepato-renal insufficiency and uncontrolled endocrine disease
* Patients on anti-depressant, anti-anxiety, anti-convulsant and anti-parkinsonism medications
* Preoperative haemoglobin \< 8 gm % and serum albumin \< 3.5mg/dl
* Patient inability to give informed consent
* Presence of preoperative delirium as assessed by 4A'S Test (score ≥ 4)

Where it's running

• Sir Ganga Ram Hospital
  New Delhi, National Capital Territory of Delhi, India Recruiting
• Sir Ganga Ram Hospital
  New Delhi, India Not yet recruiting

Study contacts

• Principal investigator: Nitin Sethi, MBBS, DNB — Sir Ganga Ram Hospital
• Study coordinator: Bimla Sharma, MBBS, DGO, MD, FICA, MHA
• Email: bimsharma1@gmail.com
• Phone: 00911142252523

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.