Understanding Post-Intensive Care Syndrome in ICU patients
Improving Intensive Care Through Biobanking: a Strategic Approach to Understanding Post-Intensive Care Syndrome
Medical University of Vienna · NCT06671795
This study looks at how surviving an ICU stay affects the physical and mental health of adult patients over time and tries to find links to specific biological markers.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Medical University of Vienna (other) |
| Locations | 1 site (Vienna) |
| Trial ID | NCT06671795 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the development and progression of Post-Intensive Care Syndrome (PICS) in adult ICU patients by creating a biobank of biological samples and outcome data. It focuses on the physical, cognitive, and psychological health outcomes of ICU survivors and their relationship with potential biomarkers. Participants will provide blood samples during their ICU stay and at follow-up visits, while also completing assessments to measure their quality of life and health outcomes over time. The study seeks to identify the incidence of PICS and associated risk factors six months post-ICU discharge.
Who should consider this trial
Good fit: Ideal candidates are adult ICU patients aged 18-65 who have been admitted to the ICU for at least 48 hours.
Not a fit: Patients who are transferred from another ICU, have a legal guardian, are homeless, or reside outside of Austria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of long-term health outcomes for ICU survivors.
How similar studies have performed: Other studies have explored similar outcomes in ICU patients, but this biobank approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ICU stay of at least 48 hours * Age between 18 and 65 years at the time of ICU admission * Written informed consent Exclusion Criteria: * Transfer from another ICU outside of the Medical University of Vienna * Patient with a legal guardian * Homelessness * Place of residence outside of Austria
Where this trial is running
Vienna
- Medical University of Vienna — Vienna, Austria (RECRUITING)
Study contacts
- Study coordinator: Akos Tiboldi, Dr.med.univ.
- Email: akos.tiboldi@meduniwien.ac.at
- Phone: +4314040041000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Post-Intensive Care Syndrome, ICU Biobank, Long-term ICU outcomes, Cognitive impairment, Physical impairment, Psychological impairment, Health-related quality of life, Epigenetics in critical care