Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding persistent pain after thoracoabdominal aorta surgery

Official title: Characterising the Phenotype for Persistent Postoperative Pain Following Repair of the Thoraco-abdominal Aorta

Run by Queen Mary University of London · NCT05369130 · Data updated 2026-11-12

This study is trying to understand why some people have ongoing pain after thoracoabdominal aorta surgery to find out what might help prevent it.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorQueen Mary University of London
Academic / other
Locations1 site (London)
StatusRecruiting
StartedJune 12, 2022
Main results expectedJanuary 31, 2029
Study endsFebruary 2029
Registry record updatedMarch 16, 2026
Trial IDNCT05369130 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years old who are scheduled for elective repair of the thoracoabdominal aorta.

Probably not a fit

Patients who are unwilling or unable to give consent or are under 18 years of age will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the understanding of patients who experience persistent postsurgical pain following thoracoabdominal aorta surgery. It will involve a prospective biopsychosocial characterization of patients undergoing this operation, focusing on the mechanisms that contribute to long-term pain. The study seeks to identify factors that may influence the development of persistent pain, as current methods for prevention are lacking. By examining this surgical cohort, the research hopes to shed light on the complexities of pain management in this population.

Why it matters

Potential benefit: If successful, this study could lead to improved strategies for preventing and managing persistent postsurgical pain in patients undergoing thoracoabdominal aorta surgery.

How similar studies have gone: While there is growing awareness of persistent pain after surgery, this specific approach to understanding its mechanisms in thoracoabdominal aorta surgery is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults (over 18 years of age) undergoing elective repair of the thoraco-abdominal aorta. Able to adequately understand and respond to verbal instructions

Exclusion Criteria:

* Unwilling or unable to give consent, Age \<18 years

Where it's running

  • St Bartholomew's Hospital
    London, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.