Understanding persistent pain after thoracoabdominal aorta surgery
Official title: Characterising the Phenotype for Persistent Postoperative Pain Following Repair of the Thoraco-abdominal Aorta
Run by Queen Mary University of London · NCT05369130 · Data updated 2026-11-12
This study is trying to understand why some people have ongoing pain after thoracoabdominal aorta surgery to find out what might help prevent it.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Queen Mary University of London Academic / other |
| Locations | 1 site (London) |
| Status | Recruiting |
| Started | June 12, 2022 |
| Main results expected | January 31, 2029 |
| Study ends | February 2029 |
| Registry record updated | March 16, 2026 |
| Trial ID | NCT05369130 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who are scheduled for elective repair of the thoracoabdominal aorta.
✕Probably not a fit
Patients who are unwilling or unable to give consent or are under 18 years of age will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to enhance the understanding of patients who experience persistent postsurgical pain following thoracoabdominal aorta surgery. It will involve a prospective biopsychosocial characterization of patients undergoing this operation, focusing on the mechanisms that contribute to long-term pain. The study seeks to identify factors that may influence the development of persistent pain, as current methods for prevention are lacking. By examining this surgical cohort, the research hopes to shed light on the complexities of pain management in this population.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for preventing and managing persistent postsurgical pain in patients undergoing thoracoabdominal aorta surgery.
How similar studies have gone: While there is growing awareness of persistent pain after surgery, this specific approach to understanding its mechanisms in thoracoabdominal aorta surgery is novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (over 18 years of age) undergoing elective repair of the thoraco-abdominal aorta. Able to adequately understand and respond to verbal instructions Exclusion Criteria: * Unwilling or unable to give consent, Age \<18 years
Where it's running
-
St Bartholomew's Hospital
London, United Kingdom Recruiting
Study contacts
- Study coordinator: Brian Herath, MBBS
- Email: b.herath@nhs.net
- Phone: 00447870681640
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.