Understanding patient expectations before treating Lyme disease symptoms

Impact of Patient's Pretreatment Expectations on Treatment Outcome of Early Lyme Borreliosis

NA · University Medical Centre Ljubljana · NCT03462329

This study looks at how what patients expect from treatment affects their experience with symptoms after being treated for Lyme disease.

Quick facts

PhaseNA
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Medical Centre Ljubljana (other)
Locations1 site (Ljubljana)
Trial IDNCT03462329 on ClinicalTrials.gov

What this trial studies

This study investigates how patients' expectations about treatment outcomes influence their experiences with post-Lyme symptoms after being treated for early Lyme disease, specifically erythema migrans. Patients will complete a questionnaire to quantify their pretreatment expectations, which will then be correlated with their treatment outcomes. Additionally, the study will compare the prevalence of nonspecific symptoms in these patients to age-matched controls who do not have a history of Lyme disease.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with erythema migrans due to early Lyme disease.

Not a fit: Patients who are pregnant, lactating, immunocompromised, or have recently taken antibiotics with antiborrelial activity may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help tailor treatment approaches based on patient expectations, potentially improving outcomes for those with Lyme disease.

How similar studies have performed: While this approach is relatively novel, similar studies have explored the impact of patient expectations on treatment outcomes in other conditions, showing promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* erythema migrans

Exclusion Criteria:

* pregnancy or lactation
* immunocompromised
* taking antibiotic with antiborrelial activity within 10 days

Where this trial is running

Ljubljana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Erythema Migrans, Post-Lyme symptoms, Pretreatment expectations

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.