Clinical trial Recruiting at 1 site Observational Ages 12 to 120

Understanding pain and its disorders through participant experiences

Official title: Clinical and Scientific Assessment of Pain and Painful Disorders

Run by National Institutes of Health Clinical Center (CC) · NCT02707029 · Data updated 2026-11-12

This study is trying to understand how people experience pain by looking at both those with pain disorders and those without, to help improve future pain research.

Quick facts

Study typeObservational
Ages12 Years to 120 Years
SexAll
Enrollment10000 (estimated)
SponsorNational Institutes of Health Clinical Center (CC)
NIH
Locations1 site (Bethesda, Maryland)
StatusRecruiting
StartedJuly 22, 2016
Main results expectedFebruary 9, 2027
Study endsFebruary 9, 2027
Registry record updatedOctober 13, 2026
Trial IDNCT02707029 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals aged 12 years and older, both with and without pain disorders.

Probably not a fit

Patients with acute medical or psychiatric issues that could interfere with study procedures may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the experience of pain by assessing individuals with and without pain disorders. Participants aged 12 and older will undergo a screening process that includes medical history, physical exams, questionnaires, and MRI scans while experiencing various sensations. The study seeks to create detailed phenotypic descriptions of pain disorders and determine eligibility for other NIH research protocols focused on pain. By collecting comprehensive data, researchers hope to enhance the understanding of pain and its clinical aspects.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and treatment options for individuals suffering from pain disorders.

How similar studies have gone: Other studies have shown success in understanding pain through similar observational approaches, making this a promising area of research.

Who can join: the full rules

Show full inclusion / exclusion criteria
* INCLUSION CRITERIA:
* Are \>= 12 years of age

EXCLUSION CRITERIA:

* Have difficulties with communication that make subjective pain assessment impossible or unreliable.
* Have acute medical or psychiatric health issues that create additional and substantial adverse risks related to study procedures. Medical examples are the acute complications of medical disease, such as asymptomatic hypertensive urgency, diabetic ketoacidosis, symptomatic hyperthyroidism, and unstable angina. Psychiatric examples are the acute complications of psychiatric disease, such as acute mania, paranoid delusions, or having acute panic attacks.
* Are participating in other ongoing research protocols such that phenotypic measurements would interfere with the conduct of an ongoing protocols or the receipt of a research treatment would influence the phenotypic measurements.
* Employees or staff that work at NCCIH.
* Pregnant women

Where it's running

  • National Institutes of Health Clinical Center
    Bethesda, Maryland, United States
    Recruiting

Study contacts

  • Principal investigator: Miroslav Backonja, M.D. — National Center for Complementary and Integrative Health (NCCIH)
  • Study coordinator: Keyonna L Berry
  • Email: keyonna.berry@nih.gov
  • Phone: (301) 594-1782

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.