Understanding outcomes for survivors of sinonasal and nasopharyngeal tumors
Assessment of Functional and Symptom Outcomes for Survivors of Paranasal Sinus, Nasopharyngeal and Skull Base Tumors
This study is trying to understand the symptoms and challenges faced by people who have survived sinonasal or nasopharyngeal cancer to help improve their health and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | M.D. Anderson Cancer Center Academic / other |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT05733091 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the symptoms and functional changes experienced by patients undergoing treatment for sinonasal or nasopharyngeal cancer. It will estimate the prevalence and severity of adverse outcomes in survivors of both benign and malignant tumors in these areas. Additionally, the study seeks to identify health promotion behaviors and predictors of survivorship outcomes, while developing a comprehensive database of patient-reported outcomes and clinical data. The research will focus on evaluating the utility of these outcomes in understanding the functional impairments and symptom burden faced by patients.
Who should consider this trial
Good fit: Ideal candidates include previously untreated adults aged 18 and older with a diagnosis or suspicion of sinonasal or nasopharyngeal malignancy.
Not a fit: Patients with a history of previous malignancies (other than treated skin cancers) or existing neurocognitive impairments unrelated to their current condition may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of survivorship outcomes and improve care strategies for patients with sinonasal and nasopharyngeal tumors.
How similar studies have performed: While this study addresses a specific patient population, similar studies have shown success in understanding survivorship outcomes in cancer patients, indicating potential for valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: 1. Previously untreated patients with or suspected to have sinonasal malignancy or nasopharyngeal malignancy diagnosis based on either outside pathology report or MD Anderson pathology report. 2. Age ≥ 18 years 3. Plan to obtain the majority of treatment at MDACC including surgery and radiotherapy 4. Ability to understand and willingness to sign written informed consent Exclusion criteria: 1. History of the previous solid or liquid malignancies, apart from skin cancers treated with local therapy. 2. Existing neurocognitive impairment that is not the result of sinonasal and nasopharyngeal cancers or is treatment. 3. Previous treatment for sinonasal or nasopharyngeal carcinomas, apart from biopsy.
Where this trial is running
Houston, Texas
- M D Anderson Cancer Center — Houston, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Shirley Su, MBBS — M.D. Anderson Cancer Center
- Study coordinator: Shirley Su, MBBS
- Email: sysu@mdanderson.org
- Phone: (713) 792-4720
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.