Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding oropharyngeal carcinoma and its connection to HPV

Official title: Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma

Run by Stanford University · NCT05880797 · Data updated 2026-11-12

This study is trying to learn more about oropharyngeal cancer and its link to HPV by collecting blood samples from patients to see how the disease changes over time.

More Human Papilloma Virus trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorStanford University
Academic / other
Locations1 site (Palo Alto, California)
StatusRecruiting
StartedJuly 7, 2023
Main results expectedAugust 2027
Study endsAugust 2027
Registry record updatedSeptember 15, 2026
Trial IDNCT05880797 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with oropharyngeal carcinoma or those with HPV-associated cancer of unknown primary origin.

Probably not a fit

Patients who are not willing to sign consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the understanding of the natural history of oropharyngeal carcinoma (OPC), particularly in relation to human papilloma virus (HPV). Researchers will collect blood samples from patients diagnosed with OPC before treatment and at six follow-up time points to analyze changes over time. The study focuses on both HPV-associated and non-associated cases to provide a comprehensive profile of the disease. By gathering this data, the study seeks to uncover insights that could inform future treatment strategies.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of oropharyngeal carcinoma, potentially enhancing patient outcomes.

How similar studies have gone: While this study employs a novel approach to profiling OPC, similar studies have shown promise in understanding cancer biology and patient outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with oropharyngeal carcinoma or patients with cancer of the unknown primary that is HPV associated, or possibly deemed to be originating from the oropharynx.

Exclusion Criteria:

* Not willing to sign consent

Where it's running

  • Stanford University
    Palo Alto, California, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.