Understanding Occupational Therapy for Children with Autism

Characterizing Occupational Therapy Intervention for Children With Autism Spectrum

Observational Ohio State University · NCT05480605

This study is testing how occupational therapy helps children with autism improve their attention and sensory processing over several weeks.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages6 Years to 13 Years
SexAll
SponsorOhio State University Academic / other
Locations2 sites (Columbus, Ohio and 1 other locations)
Trial IDNCT05480605 on ClinicalTrials.gov

What this trial studies

This pilot study investigates how occupational therapy impacts sensory processing and attention in children with autism spectrum disorders. It focuses on measuring behavioral and neural responses, particularly through electroencephalography (EEG), to assess the effectiveness of therapy sessions. Over 6-8 weeks, 30 children aged 6-13 will participate in weekly therapy sessions, with the study aiming to establish the role of child engagement as a predictor of therapeutic outcomes. The findings could provide insights into the neural mechanisms underlying occupational therapy interventions.

Who should consider this trial

Good fit: Ideal candidates include children aged 6-13 with a medical diagnosis of autism who are verbal and have normal or corrected vision/hearing.

Not a fit: Patients with a history of severe neurological disorders, major visual impairments, or chronic medical conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the effectiveness of occupational therapy for children with autism by identifying key factors that improve engagement and outcomes.

How similar studies have performed: While occupational therapy is widely used, this specific approach examining EEG measures in relation to therapy engagement is novel and has not been extensively tested in previous studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

For children with autism:

* a medical diagnosis of Autism
* between 8 - 13 years
* must be verbal
* have normal or corrected vision/hearing
* enrollment in the 8-week OT treatment plan with a therapist enrolled in the study.

For typically developing children:

• No history of neurological injuries, disabilities, and family history of mental health disorders on parent report

Exclusion Criteria:

* history of a definitive neurologic disorder including seizures (except for uncomplicated brief febrile seizures), tumor, severe head injury, stroke, lesion, or disease
* presence of a severe chronic medical disorder
* presence of a major visual impairment
* history of alcohol/substance abuse or dependency.

Where this trial is running

Columbus, Ohio and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Autism Spectrum DisorderOccupational TherapyEngagementAutism Spectrum DisordersEEG/ERP
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.