Understanding Neurologic Events After Surgery for Moyamoya Disease
MagNETs- Managing Transient Neurologic Episodes in Surgery for Moyamoya Disease
This study looks at how often patients with Moyamoya Disease experience temporary neurological issues after surgery and what might help reduce these problems during recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 88 (estimated) |
| Ages | 3 Years and up |
| Sex | All |
| Sponsor | Stanford University Academic / other |
| Locations | 1 site (Palo Alto, California) |
| Trial ID | NCT06880341 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the occurrence of post-operative Transient Neurologic Events (TNEs) in patients with Moyamoya Disease within 30 days following surgery. It will collect data on various interventions and assessments during the recovery period to identify factors contributing to TNEs and explore strategies for their reduction. The study will utilize clinical neurological scales to evaluate patient outcomes weekly post-surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with Moyamoya Disease who are undergoing direct extracranial-intracranial bypass surgery and are over the age of 3.
Not a fit: Patients with renal dysfunction, electrolyte disturbances, neuromuscular disorders, or heart block may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management and outcomes for patients undergoing surgery for Moyamoya Disease by reducing the incidence of neurologic complications.
How similar studies have performed: While the specific approach of this study is observational, similar studies focusing on post-operative complications in neurosurgery have shown success in identifying risk factors and improving patient outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Moyamoya Disease (MMD) patients undergoing direct extracranial-intracranial (ECIC) bypass. Patients above the age of 3 years old are eligible for the study Exclusion Criteria: * Renal dysfunction, electrolyte disturbances neuromuscular disorders including Myaesthenia Gravis, heart block
Where this trial is running
Palo Alto, California
- Stanford University Hospital — Palo Alto, California, United States (Recruiting)
Study contacts
- Study coordinator: Jinendra Ekanayake
- Email: jine7000@stanford.edu
- Phone: 650-660-1266
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.