Understanding Neurologic Events After Surgery for Moyamoya Disease
Official title: MagNETs- Managing Transient Neurologic Episodes in Surgery for Moyamoya Disease
Run by Stanford University · NCT06880341 · Data updated 2026-11-12
This study looks at how often patients with Moyamoya Disease experience temporary neurological issues after surgery and what might help reduce these problems during recovery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 3 Years and up |
| Sex | All |
| Enrollment | 88 (estimated) |
| Sponsor | Stanford University Academic / other |
| Locations | 1 site (Palo Alto, California) |
| Status | Recruiting |
| Started | May 21, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | March 31, 2027 |
| Registry record updated | May 28, 2025 |
| Trial ID | NCT06880341 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with Moyamoya Disease who are undergoing direct extracranial-intracranial bypass surgery and are over the age of 3.
✕Probably not a fit
Patients with renal dysfunction, electrolyte disturbances, neuromuscular disorders, or heart block may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the occurrence of post-operative Transient Neurologic Events (TNEs) in patients with Moyamoya Disease within 30 days following surgery. It will collect data on various interventions and assessments during the recovery period to identify factors contributing to TNEs and explore strategies for their reduction. The study will utilize clinical neurological scales to evaluate patient outcomes weekly post-surgery.
Why it matters
Potential benefit: If successful, this study could lead to improved management and outcomes for patients undergoing surgery for Moyamoya Disease by reducing the incidence of neurologic complications.
How similar studies have gone: While the specific approach of this study is observational, similar studies focusing on post-operative complications in neurosurgery have shown success in identifying risk factors and improving patient outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Moyamoya Disease (MMD) patients undergoing direct extracranial-intracranial (ECIC) bypass. Patients above the age of 3 years old are eligible for the study Exclusion Criteria: * Renal dysfunction, electrolyte disturbances neuromuscular disorders including Myaesthenia Gravis, heart block
Where it's running
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Stanford University Hospital
Palo Alto, California, United States Recruiting
Study contacts
- Study coordinator: Jinendra Ekanayake
- Email: jine7000@stanford.edu
- Phone: 650-660-1266
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Ischemic preconditioning to reduce ischemic events in Moyamoya with standard care
This study tests whether remote ischemic conditioning can lower stroke risk for adults with Moyamoya disease who are receiving standard medical care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.