Understanding musculoskeletal health and wellbeing
Investigating Musculoskeletal Health and Wellbeing: A Cohort Study
This study is trying to understand how musculoskeletal pain, frailty, and disability change over time in 10,000 adults by collecting information through questionnaires for up to five years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Nottingham Academic / other |
| Locations | 1 site (Nottingham) |
| Trial ID | NCT03696134 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the progression and associations of musculoskeletal pain, frailty, and disability among a cohort of 10,000 individuals aged 18 and older. Participants will be recruited from general practice surgeries, secondary care, and the general public, with data collected through questionnaires at baseline and annual follow-ups for up to five years. The study will assess various factors including pain severity, distribution, quality, fracture risks, and frailty using established scales and criteria. The goal is to identify different phenotypes of frailty, pain, and disability and their interrelations.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 18 and older who are at risk of or currently experiencing musculoskeletal frailty, pain, or disability.
Not a fit: Patients with serious mental illness, dementia, or those receiving dialysis or home oxygen may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of musculoskeletal health, leading to improved management and treatment strategies for patients experiencing pain and disability.
How similar studies have performed: While there have been studies on musculoskeletal health, this specific approach to characterizing phenotypes through a large cohort is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Ability to give informed consent. Aged 18 and over Frailty score of ≥ 0.12 on the eFI Have or are at risk of developing musculoskeletal frailty, pain or disability Exclusion Criteria: \- Inadequate understanding of verbal explanations or written information in English; Special communication needs; Receiving dialysis; Receiving home oxygen; Terminal cancer; Unstable angina or heart failure; Serious mental illness; Dementia.
Where this trial is running
Nottingham
- University of Nottingham — Nottingham, United Kingdom (Recruiting)
Study contacts
- Principal investigator: David Walsh — University of Nottingham
- Study coordinator: Bonnie Millar
- Email: bonnie.millar@nottingham.ac.uk
- Phone: 0115 8231754
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.