Understanding muscle power and control to prevent falls in knee osteoarthritis patients
Analisi Della Perdita di Forza e Potenza Muscolare e Del Degrado Del Controllo Motorio Per la Predizione Delle Cadute in Una Popolazione Affetta da Artrosi di Ginocchio
This study is trying to see if measuring muscle power and control can better predict fall risks in older adults with knee osteoarthritis than just looking at muscle strength alone.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 65 Years to 80 Years |
| Sex | All |
| Sponsor | Istituto Ortopedico Rizzoli Academic / other |
| Locations | 1 site (Bologna) |
| Trial ID | NCT06611618 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the relationship between muscle power, strength, and motor control degradation in predicting fall risks among elderly patients with knee osteoarthritis. Participants will undergo various assessments, including muscle force and power evaluations using a dynamometer, home-based mobility monitoring, and MRI scans of the lower limbs. The goal is to determine if muscle power and motor control are more effective predictors of falls than muscle strength alone. Data will be collected over 24 months through multiple visits to monitor changes and inform strategies for fall prevention.
Who should consider this trial
Good fit: Ideal candidates are elderly individuals aged 65 to 80 with knee osteoarthritis and no history of falls in the past year.
Not a fit: Patients with significant comorbidities or conditions that affect muscle function or MRI compatibility may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved fall prevention strategies for elderly patients with knee osteoarthritis.
How similar studies have performed: While the approach of assessing muscle power and control in relation to fall risk is innovative, similar studies have shown promise in understanding fall risks in elderly populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 65 and 80 years * Kellgren score II e III * No history of falls in the last 12 months Exclusion Criteria: * Any musculoskeletal, neurological, rheumatic or tumoral diseases * Dementia * Diabetes * Inguinal or abdominal hernia * Severe Hypertension (Level 3) * Severe Cardio-pulmonary insufficiency * Diagnosis of Osteonecrosis in the lower limb joints * Pathologies or physical conditions incompatible with the use of magnetic resonance imaging and electrostimulation (i.e., active and passive implanted biomedical devices, epilepsy, severe venous insufficiency in the lower limbs) * Previous interventions or traumas to the joints of the lower limb
Where this trial is running
Bologna
- IRCCS Istituto Ortopedico Rizzoli — Bologna, Italy (Recruiting)
Study contacts
- Principal investigator: Lisa Berti, Professor — IRCCS Istituto Ortopedico Rizzoli
- Study coordinator: Lisa Berti, Professor
- Email: lisa.berti@ior.it
- Phone: +390516366529
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.