Understanding muscle power and control to prevent falls in knee osteoarthritis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the relationship between muscle power, strength, and motor control degradation in predicting fall risks among elderly patients with knee osteoarthritis. Participants will undergo various assessments, including muscle force and power evaluations using a dynamometer, home-based mobility monitoring, and MRI scans of the lower limbs. The goal is to determine if muscle power and motor control are more effective predictors of falls than muscle strength alone. Data will be collected over 24 months through multiple visits to monitor changes and inform strategies for fall prevention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 65 and 80 years
* Kellgren score II e III
* No history of falls in the last 12 months

Exclusion Criteria:

* Any musculoskeletal, neurological, rheumatic or tumoral diseases
* Dementia
* Diabetes
* Inguinal or abdominal hernia
* Severe Hypertension (Level 3)
* Severe Cardio-pulmonary insufficiency
* Diagnosis of Osteonecrosis in the lower limb joints
* Pathologies or physical conditions incompatible with the use of magnetic resonance imaging and electrostimulation (i.e., active and passive implanted biomedical devices, epilepsy, severe venous insufficiency in the lower limbs)
* Previous interventions or traumas to the joints of the lower limb

Where it's running

• IRCCS Istituto Ortopedico Rizzoli
  Bologna, Italy Recruiting

Study contacts

• Principal investigator: Lisa Berti, Professor — IRCCS Istituto Ortopedico Rizzoli
• Study coordinator: Lisa Berti, Professor
• Email: lisa.berti@ior.it
• Phone: +390516366529

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.