Understanding long-term effects of leptospirosis in Reunion
Chronic Post-leptospirosis Manifestations in Reunion
NA · Centre Hospitalier Universitaire de la Réunion · NCT05436756
This study is trying to see how leptospirosis affects people long after they've been treated for it, focusing on those in Reunion who have had the disease.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 198 (estimated) |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de la Réunion (other) |
| Locations | 4 sites (Saint-Paul and 3 other locations) |
| Trial ID | NCT05436756 on ClinicalTrials.gov |
What this trial studies
This study investigates the chronic manifestations of leptospirosis in patients who have been previously diagnosed and treated for the disease. It involves biological sampling and the collection of data through telephone questionnaires to assess the ongoing health impacts of leptospirosis. The research aims to gather insights into the prevalence and severity of post-leptospirosis symptoms in the Reunion region, where the disease is endemic. By focusing on a cohort of patients from the COLEPT study, the trial seeks to enhance understanding of this public health issue.
Who should consider this trial
Good fit: Ideal candidates include adults and children who have been hospitalized for confirmed leptospirosis within the last 12-18 months and reside in Reunion.
Not a fit: Patients who have not been diagnosed with leptospirosis or those unable to participate due to severe health conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management and treatment strategies for patients suffering from long-term effects of leptospirosis.
How similar studies have performed: While there is limited data on similar studies specifically addressing chronic manifestations of leptospirosis, the approach of investigating long-term effects of infectious diseases has shown promise in other contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult or child subjects having been included in the COLEPT cohort with confirmed leptospirosis Where * Adult subjects or children hospitalized for leptospirosis confirmed within 12-18 months before LEPTONIC inclusion; * Be resident in Reunion * Ability to answer a telephone questionnaire * Benefit from a social security scheme Exclusion Criteria: * Refusal of participation by the patient or his entourage if the patient is physically unable to give his opinion (coma, resuscitation, etc.). * Exclusion or premature termination of participation in the COLEPT cohort * Patient under judicial safeguard, guardianship or curatorship, under activated future protection mandate and family authorization
Where this trial is running
Saint-Paul and 3 other locations
- CHOR — Saint-Paul, France (RECRUITING)
- DIALLO — Saint-Pierre, France (RECRUITING)
- GHER — Saint-Benoît, Reunion (RECRUITING)
- CHU de la Réunion — Saint-Denis, Reunion (RECRUITING)
Study contacts
- Study coordinator: Loic RAFFRAY, Dr
- Email: loic.raffray@chu-reunion.fr
- Phone: +262 262 90 50 50
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Leptospirosis