Understanding Intracranial Artery Dissection and its Impact on Stroke
International Intracranial Artery Dissection Study
Insel Gruppe AG, University Hospital Bern · NCT02756091
This study is trying to learn more about intracranial artery dissection, a cause of stroke in young adults, to better understand its effects and how to manage it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Insel Gruppe AG, University Hospital Bern (other) |
| Locations | 3 sites (Osaka, Kansai and 2 other locations) |
| Trial ID | NCT02756091 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather comprehensive data on intracranial artery dissection (IAD), a significant cause of stroke in young adults. It focuses on the natural history, risk factors, and outcomes associated with IAD, particularly in non-Asian populations, where data is limited. By analyzing cases of acute IAD within 30 days of symptom onset, the study seeks to improve understanding of this condition and its management. The research involves collaboration among multiple institutions to ensure a diverse and representative patient population.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have experienced acute intracranial artery dissection within the last 30 days.
Not a fit: Patients with iatrogenic dissection or those with extracranial dissection extending into the intracranial space may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management strategies for patients suffering from intracranial artery dissection.
How similar studies have performed: While there have been numerous studies on cervical artery dissection, this study's focus on intracranial artery dissection is relatively novel and underexplored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with acute Intracranial Artery Dissection (symptom onset ≤ 30 days) * Age ≥ 18 years * Consent to participate according to local requirements Exclusion Criteria: * Iatrogenic dissection caused by endovascular intervention * Extracranial dissection with intracranial extension
Where this trial is running
Osaka, Kansai and 2 other locations
- National Cerebral and Cardiovascular Center Osaka — Osaka, Kansai, Japan (RECRUITING)
- Department of Neurology, University Hospital Basel — Basel, Canton of Basel-City, Switzerland (RECRUITING)
- Department of Neurology, Inselspital Bern — Bern, Switzerland (RECRUITING)
Study contacts
- Principal investigator: Marcel Arnold, Prof. Dr. med. — Neurology Department, Inselspital University Hospital Bern
- Study coordinator: Marcel Arnold, Prof. Dr. med.
- Email: marcel.arnold@insel.ch
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cerebrovascular Disorders, Vascular: Intracranial, Intimal Dissection, Stroke, Intracranial Artery Dissection, IAD, Observational Study