Understanding Intracranial Artery Dissection and its Impact on Stroke
Official title: International Intracranial Artery Dissection Study
Run by Insel Gruppe AG, University Hospital Bern · NCT02756091 · Data updated 2026-11-12
This study is trying to learn more about intracranial artery dissection, a cause of stroke in young adults, to better understand its effects and how to manage it.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Insel Gruppe AG, University Hospital Bern Academic / other |
| Locations | 3 sites (Osaka, Kansai and 2 other locations) |
| Status | Recruiting |
| Started | August 2016 |
| Main results expected | November 30, 2026 |
| Study ends | November 30, 2027 |
| Registry record updated | November 13, 2024 |
| Trial ID | NCT02756091 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have experienced acute intracranial artery dissection within the last 30 days.
✕Probably not a fit
Patients with iatrogenic dissection or those with extracranial dissection extending into the intracranial space may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to gather comprehensive data on intracranial artery dissection (IAD), a significant cause of stroke in young adults. It focuses on the natural history, risk factors, and outcomes associated with IAD, particularly in non-Asian populations, where data is limited. By analyzing cases of acute IAD within 30 days of symptom onset, the study seeks to improve understanding of this condition and its management. The research involves collaboration among multiple institutions to ensure a diverse and representative patient population.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management strategies for patients suffering from intracranial artery dissection.
How similar studies have gone: While there have been numerous studies on cervical artery dissection, this study's focus on intracranial artery dissection is relatively novel and underexplored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with acute Intracranial Artery Dissection (symptom onset ≤ 30 days) * Age ≥ 18 years * Consent to participate according to local requirements Exclusion Criteria: * Iatrogenic dissection caused by endovascular intervention * Extracranial dissection with intracranial extension
Where it's running
-
National Cerebral and Cardiovascular Center Osaka
Osaka, Kansai, Japan Recruiting -
Department of Neurology, University Hospital Basel
Basel, Canton of Basel-City, Switzerland Recruiting -
Department of Neurology, Inselspital Bern
Bern, Switzerland Recruiting
Study contacts
- Principal investigator: Marcel Arnold, Prof. Dr. med. — Neurology Department, Inselspital University Hospital Bern
- Study coordinator: Marcel Arnold, Prof. Dr. med.
- Email: marcel.arnold@insel.ch
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.