Understanding idiopathic generalized epilepsy syndromes
Idiopathic Generalized Epilepsy Syndromes: Clinical Features and Long-term Outcomes
Second Affiliated Hospital, School of Medicine, Zhejiang University · NCT06388174
This study looks at different types of idiopathic generalized epilepsy to see how they affect patients and what treatments might work best for them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 4 Years to 40 Years |
| Sex | All |
| Sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University (other) |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT06388174 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on idiopathic generalized epilepsies (IGEs), including childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy, and generalized tonic-clonic seizures. It aims to describe the clinical features, electroencephalographic findings, imaging results, and long-term prognosis of patients diagnosed with IGEs. By collecting comprehensive clinical information and conducting 24-hour video-electroencephalography, the study seeks to inform optimal treatment strategies and improve patient outcomes. The findings will also address the rates of drug-resistant epilepsy and common comorbidities associated with these syndromes.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with newly diagnosed or established idiopathic generalized epilepsy as per the 2022 diagnostic criteria.
Not a fit: Patients with other epilepsy syndromes or those lost to follow-up may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the diagnosis and treatment of idiopathic generalized epilepsy, leading to better management and outcomes for patients.
How similar studies have performed: While there have been studies on epilepsy, this specific focus on idiopathic generalized epilepsy syndromes using the latest diagnostic criteria is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients are consecutively and prospectively enrolled from epilepsy center, with newly diagnosed epilepsy or established epilepsy. * Patients have a diagnosis of idiopathic generalized epilepsy (IGE), according to the 2022 diagnostic criteria. * Comprehensive clinical information is collected, and 24 hour video-electroencephalography is performed. * Sign the informed consent forms. Exclusion Criteria: * Other epilepsy syndromes are considered during follow-up, such as genetic generalized epilepsy. * Lost to follow-up
Where this trial is running
Hangzhou, Zhejiang
- 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China — Hangzhou, Zhejiang, China (RECRUITING)
Study contacts
- Principal investigator: Chunhong Shen — Second Affiliated Hospital, School of Medicine, Zhejiang University
- Study coordinator: Chunhong Shen
- Email: shen_neurology@zju.edu.cn
- Phone: +86 0571 87783872
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Epilepsy, Epilepsy, Idiopathic Generalized