Understanding how well patients tolerate and adhere to oral antibiotics for bone and joint infections
Compliance and Tolerance to Oral AntiBiotherapy in Osteoarticular Infections
This study is trying to see how well patients with bone and joint infections can handle and stick to their oral antibiotic treatment over six weeks.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Lyon) |
| Trial ID | NCT05202964 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients diagnosed with osteoarticular infections who are undergoing treatment with oral antibiotics for at least six weeks. It aims to assess the tolerance and adherence to antibiotic therapy, which is crucial given the potential for severe adverse effects and the complexity of treatment regimens. By monitoring patients' experiences, the study seeks to identify factors that influence compliance and the overall impact on treatment outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older diagnosed with osteoarticular infections requiring oral antibiotic treatment for a minimum of six weeks.
Not a fit: Patients receiving only parenteral antibiotics or those without a defined end date for oral antibiotic treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve treatment adherence and reduce adverse effects for patients with bone and joint infections.
How similar studies have performed: While there is existing literature on antibiotic adherence, this specific observational approach focusing on bone and joint infections may provide novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥ 18 years * Diagnosis of osteoarticular infection * Treatment with at least one oral antibiotic for a minimum expected duration ≥ 6 weeks with an expected end of treatment date * Patient who was informed and did not object to participate in the study Exclusion Criteria: * Treatment for BJI with oral antibiotic without end of treatment date * treatment for BJI with parenteral antibiotic only * patient who doesn't have a telephone number or who doesn't want to give it * Adults subject to a legal protection measure * Pregnant or breastfeeding women
Where this trial is running
Lyon
- Hospices Civils de Lyon — Lyon, France (Recruiting)
Study contacts
- Principal investigator: Valérie MIRABET — Hospices Civils de Lyon
- Study coordinator: Tristan FERRY, MD, PHD
- Email: tristan.ferry@chu-lyon.fr
- Phone: 4 26 73 29 38
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.