Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding how well patients tolerate and adhere to oral antibiotics for bone and joint infections

Official title: Compliance and Tolerance to Oral AntiBiotherapy in Osteoarticular Infections

Run by Hospices Civils de Lyon · NCT05202964 · Data updated 2026-11-12

This study is trying to see how well patients with bone and joint infections can handle and stick to their oral antibiotic treatment over six weeks.

More Drug-Related Side Effects and Adverse Reactions trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorHospices Civils de Lyon
Academic / other
Locations1 site (Lyon)
StatusRecruiting
StartedJune 13, 2024
Main results expectedSeptember 13, 2028
Study endsSeptember 13, 2028
Registry record updatedOctober 13, 2026
Trial IDNCT05202964 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older diagnosed with osteoarticular infections requiring oral antibiotic treatment for a minimum of six weeks.

Probably not a fit

Patients receiving only parenteral antibiotics or those without a defined end date for oral antibiotic treatment may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with osteoarticular infections who are undergoing treatment with oral antibiotics for at least six weeks. It aims to assess the tolerance and adherence to antibiotic therapy, which is crucial given the potential for severe adverse effects and the complexity of treatment regimens. By monitoring patients' experiences, the study seeks to identify factors that influence compliance and the overall impact on treatment outcomes.

Why it matters

Potential benefit: If successful, this study could improve treatment adherence and reduce adverse effects for patients with bone and joint infections.

How similar studies have gone: While there is existing literature on antibiotic adherence, this specific observational approach focusing on bone and joint infections may provide novel insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥ 18 years
* Diagnosis of osteoarticular infection
* Treatment with at least one oral antibiotic for a minimum expected duration ≥ 6 weeks with an expected end of treatment date
* Patient who was informed and did not object to participate in the study

Exclusion Criteria:

* Treatment for BJI with oral antibiotic without end of treatment date
* treatment for BJI with parenteral antibiotic only
* patient who doesn't have a telephone number or who doesn't want to give it
* Adults subject to a legal protection measure
* Pregnant or breastfeeding women

Where it's running

  • Hospices Civils de Lyon
    Lyon, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.