Understanding how we predict timing in speech and sounds
Language and Brain Rhythms
This study tests how well people can predict timing in sounds like speech and music based on their past experiences.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 356 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Bron) |
| Trial ID | NCT04457622 on ClinicalTrials.gov |
What this trial studies
This study investigates how individuals process complex temporal regularities in natural sensory stimuli, such as speech and music. By conducting auditory perception tasks with healthy participants, the research aims to uncover the mechanisms behind temporal prediction in everyday auditory experiences. The focus is on understanding how past experiences with sensory information influence our ability to anticipate future events. The study includes specific eligibility criteria to ensure a controlled environment for data collection.
Who should consider this trial
Good fit: Ideal candidates are healthy individuals aged 18-40 with normal hearing and registration in the French healthcare system.
Not a fit: Patients with neurological or psychiatric illnesses, severe hearing loss, or those on medications affecting the central nervous system may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of auditory processing, potentially leading to improved interventions for individuals with speech and hearing difficulties.
How similar studies have performed: While studies on auditory perception exist, this approach focusing on complex temporal regularities in natural stimuli is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: For all experiments: * 18- 40 years old * Registration with the French healthcare system * Informed consent * Normal hearing Additionally, for experiments 2,3 and 4 : \- Right handed Additionally, for experiment 3 and 4: \- French as native language Exclusion Criteria: For All Experiments: * Neurological or psychiatric illnesses or a history of such problems that could impact quality/variability of data or cooperation and retention of the subject in the study * Regular use of medications that impact the central nervous system * Regular use of medications, such as opioids and antidepressants, including SSRIs and tricyclic antidepressants * Severe hearing loss * A history of stroke or recent trauma to the head * Persons unable to adhere to abstinence from the use of drugs or alcohol the day or evening before experimental sessions * Women who are pregnant, breastfeeding, or have given birth in the last 6 months Additionally, for experiment 2,3 and 4 : * A pacemaker, insulin or other pump, neurostimulator, cochlear implants or other hearing aid, metal stents, prosthesis, or implants, intracerebral clips, implantable defibrillator, cerebral shunt or ventricular catheter, other foreign metal objects in the upper part of the body * any dental apparatus containing metal including or root canals * any foreign metallic object anywhere in the body * bolts, screws * orthopedic devices or implants Additionally, for experiment 3 and 4: * claustrophobia * glasses (given the participant cannot use contact lenses) * a head size incompatible with the use of a personalized 3D headcast or a magnetoencephalography * Persons having had any surgery prior to the study which puts them at risk for metal objects left in the body
Where this trial is running
Bron
- Centre de Recherche en Neuroscience de Lyon — Bron, France (Recruiting)
Study contacts
- Principal investigator: Anne KOSEM, PhD — Centre de recherche de Neurosciences de Lyon (CRNL)
- Study coordinator: Anne KOSEM, PhD
- Email: anne.kosem@inserm.fr
- Phone: 4.72.13.89.16
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.