Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Understanding how vision impairment affects walking over obstacles in older adults

Official title: Impact of Stepping Over Obstacles of Different Contrast and Height on Gait and Eye Movements in Older Adults With and Without Vision Impairment

Run by Indiana University · NCT05888441 · Data updated 2026-11-12

This study tests how older adults with vision impairment walk around obstacles compared to those with normal vision to find ways to help prevent falls.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorIndiana University
Academic / other
Locations1 site (Bloomington, Indiana)
StatusRecruiting
StartedApril 14, 2023
Main results expectedDecember 31, 2028
Study endsDecember 31, 2028
Registry record updatedNovember 13, 2025
Trial IDNCT05888441 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and over who can walk independently, including those with normal or impaired vision.

Probably not a fit

Patients with severe cognitive limitations, vestibular disorders, or significant walking abnormalities may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how adults with vision impairment adjust their walking behavior when navigating obstacles of varying heights and contrasts. By analyzing gait changes and gaze behavior, the research aims to identify strategies to prevent falls in individuals with low vision. Participants will include both those with normal vision and those with impaired vision, allowing for a comparative analysis of their responses to obstacles. The findings could lead to improved safety measures for older adults at risk of falls.

Why it matters

Potential benefit: If successful, this study could lead to enhanced fall prevention strategies for older adults with vision impairment.

How similar studies have gone: While studies on gait and vision have been conducted, this specific focus on obstacle negotiation in older adults with vision impairment is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 or over
* Able to walk independently
* Either have normal vision, or impaired vision.

  * Impaired vision is defined as binocular visual acuity of 20/25 or worse with or without a central scotoma; and/or binocular visual field that is restricted to an average of 100 degrees in diameter or less
  * Control subjects will have visual acuity of 20/40 or better.

Exclusion Criteria:

* Not cleared by a medical provider for moderate physical activity
* Self-report or have a history of: vestibular disorder or deafness
* Medical history of any condition that affects the ability to walk for up to 2 hours with breaks, such as feeling dizzy or faint, chest pain, palpitations, pain or numbness in the legs, shortness of breath,
* Cognitive limitations either by self-report or a score on the Mini Mental State Exam below 24 (out of 30)
* Walking or gait abnormalities, such as those caused from an injury, surgery, severe arthritis, or neurological condition such as Parkinson's disease
* Unable to walk without any walking aids such as a walker, cane, guide dog, or oxygen tank.
* Does not speak English

Where it's running

  • Indiana University
    Bloomington, Indiana, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.