Understanding how the brain learns motor-sensory skills during awake surgery
Official title: Brain Representation of Acquisition in Humans of Motor-Sensory Skills
Run by Fondation Ophtalmologique Adolphe de Rothschild · NCT05688683 · Data updated 2026-11-12
This study looks at how the brain learns to control movements and respond to sounds in patients having awake surgery for epilepsy or brain tumors.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 1 site (Paris) |
| Status | Recruiting |
| Started | January 4, 2023 |
| Main results expected | March 2028 |
| Study ends | March 2028 |
| Registry record updated | January 5, 2026 |
| Trial ID | NCT05688683 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients undergoing awake surgery for epilepsy or cerebral tumors who can benefit from intracranial brain recording.
✕Probably not a fit
Patients with complete deafness or those unable to perform the experimental task due to other impairments will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the interactions between perceptual and motor systems in the brain during the acquisition of motor-sensory skills, particularly in the context of complex tasks like speech production or playing a musical instrument. It utilizes electro-corticography to record brain activity in patients undergoing awake surgery for epilepsy or cerebral tumors, allowing researchers to analyze how the brain generates motor commands in response to sound-producing systems. The study aims to provide insights into the dynamic aspects of sensorimotor learning that have not been directly tested before.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of motor-sensory skill acquisition, potentially leading to improved rehabilitation strategies for patients with motor control impairments.
How similar studies have gone: While this approach is novel in directly testing sensorimotor learning during acoustic production tasks, similar studies have shown promise in understanding brain function during motor tasks.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Benefiting from an intracranial brain recording during a programmed surgery in awake condition. Exclusion Criteria: * Patient with complete deafness * Patient with a disorder or impairment that does not allow him/her to perform the experimental task according to the investigator's judgment
Where it's running
-
Fondation Adolphe de Rothschild
Paris, France Recruiting
Study contacts
- Study coordinator: Pierre Bourdillon, MD PHD
- Email: pbourdillon@for.paris
- Phone: +33 1 48 03 66 12
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.