Understanding how the brain acquires language through intracranial recordings
Language Acquisition in the Brain and Algorithms: Towards Systematic Monitoring of the Evolution of Semantic Representations in Biological and Artificial Neural Networks
This study is trying to see how children's brains learn language by recording their brain activity while they listen to stories and phrases.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 1 site (Paris, France) |
| Trial ID | NCT05217043 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the mechanisms of language acquisition in the brain by utilizing intracranial electroencephalography (iEEG) recordings in children with drug-resistant epilepsy. Participants will listen to pre-recorded phrases and stories while their brain activity is monitored, allowing researchers to analyze the evolution of semantic representations over time. The study focuses on understanding how the brain processes language and the development of semantic composition, which remains largely unexplored. By examining brain activity during these recordings, the study seeks to provide insights into the neural basis of language learning.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 2 to 20 years who are undergoing long-term intracranial brain recordings due to drug-resistant epilepsy.
Not a fit: Patients with complete deafness may not benefit from this study as the focus is on language acquisition through auditory stimuli.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of language acquisition, potentially leading to improved interventions for language-related disorders.
How similar studies have performed: While studies on language acquisition exist, this specific approach using intracranial recordings in children is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any patient benefiting from a long-term intracranial brain recording. * Non-opposition to participating in the study (adult patients) * Non-opposition of at least one of the holders of the exercise of parental authority (minor patients) Exclusion Criteria: * Patient with complete deafness
Where this trial is running
Paris, France
- Fondation Ophtalmologique de Rothschild — Paris, France, France (Recruiting)
Study contacts
- Study coordinator: Amélie YACHITZ
- Email: ayavchitz@for.paris
- Phone: (0)148036454
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.