Understanding how stroke affects the perception of verticality over time
Postural Alignment in Post-stroke Participants: Providing New Insights in the Time Course of a Misperception of Verticality and Its Characteristics
Universiteit Antwerpen · NCT05978596
This study looks at how stroke affects people's sense of balance and verticality over time to see how it relates to their recovery and other movement issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Universiteit Antwerpen (other) |
| Locations | 2 sites (Antwerp and 1 other locations) |
| Trial ID | NCT05978596 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the time course of verticality perception in post-stroke participants, focusing on how it interacts with spatial disorders and motor function recovery. Participants will be assessed repeatedly during the subacute phase after a stroke to evaluate their subjective visual, haptic, and postural vertical perceptions, as well as their balance and motor abilities. The study aims to provide insights into the recovery of verticality perception and its association with spatial neglect and lateropulsion, which are common after stroke.
Who should consider this trial
Good fit: Ideal candidates include individuals who have experienced a first-ever, MRI- or CT-confirmed ischemic or hemorrhagic supratentorial stroke.
Not a fit: Patients with bilateral lesions, vestibular dysfunction, or other neurological conditions that could interfere with assessments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of post-stroke recovery and improve rehabilitation strategies for patients with spatial perception issues.
How similar studies have performed: While previous studies have indicated deviations in verticality perception among post-stroke patients, this specific longitudinal approach to understanding recovery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * First-ever, MRI- or CT-confirmed, ischemic or hemorrhagic supratentorial stroke; * Able to give written informed consent. Exclusion Criteria: * Bilateral lesions; * Vestibular dysfunction, symptomatic orthostatic hypotension or other pre-existing neurological conditions that could interfere with the assessments; * Inability to understand and follow basic verbal instructions; * Hemianopsia or other visual field deficits (glasses or corrective lenses are allowed) And a group of healthy controls to obtain normative data. These participants are eligible for inclusion if they are between 18 and 90 years old and do not suffer from vestibular dysfunction, symptomatic orthostatic hypotension or other neurological conditions that could interfere with the assessment.
Where this trial is running
Antwerp and 1 other locations
- AZ Monica — Antwerp, Belgium (RECRUITING)
- RevArte — Edegem, Belgium (RECRUITING)
Study contacts
- Principal investigator: Wim Saeys, Prof. Dr. — Universiteit Antwerpen
- Study coordinator: Charlotte van der Waal, MSc
- Email: charlotte.vanderwaal@uantwerpen.be
- Phone: +3232659724
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Stroke, Perception of verticality, Spatial neglect, Lateropulsion, Postural control, Subjective Visual Vertical, Subjective Haptic Vertical, Subjective Postural Vertical