Understanding how premature infants process sounds
Official title: Neural Signatures of Processing the Temporal Features of Auditory Events: From Preterm Infancy to Adulthood
Run by Centre Hospitalier Universitaire, Amiens · NCT04270734 · Data updated 2026-11-12
This study is testing how premature babies hear and respond to sounds to better understand their brain development and any risks they might face.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 0 Days to 1 Day |
| Sex | All |
| Enrollment | 240 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Status | Recruiting |
| Started | February 1, 2020 |
| Main results expected | February 2027 |
| Study ends | February 2027 |
| Registry record updated | June 10, 2025 |
| Trial ID | NCT04270734 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are full-term neonates born between 25 and 36 weeks gestational age.
✕Probably not a fit
Patients outside the specified gestational age range will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates how premature neonates, specifically those between 25 and 36 weeks gestational age, respond to auditory stimuli using advanced techniques like High Resolution Electroencephalography (EEG) and High Density Near Infrared Spectroscopy (fNIRS). By analyzing the cortical network responses, the research aims to uncover the developmental status and functionality of neuronal networks in these infants. The findings could provide insights into the neurodevelopmental risks associated with prematurity and the establishment of appropriate responses to auditory events.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of auditory processing in premature infants, potentially leading to improved interventions for neurodevelopmental disorders.
How similar studies have gone: While similar studies have explored auditory processing in neonates, this specific approach using EEG and fNIRS in premature infants is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * full term neonates between 25 and 36 weeks gestational age Exclusion Criteria: * Neonates outside the age range
Where it's running
-
CHU Amiens
Amiens, France Recruiting
Study contacts
- Principal investigator: Ghilda Ghostine, MD — CHU Amiens
- Study coordinator: Fabrice Wallois, Pr
- Email: fabrice.wallois@u-picardie.fr
- Phone: (33)322087775
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.