Clinical trial Recruiting at 1 site Observational Ages 18 and up Men only

Understanding how obesity-related factors influence prostate cancer progression

Official title: Integrating Tissue-based Spatial Information to Elucidate How Obesity-induced Tumour Metabolites Drive Prostate Cancer Progression

Run by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · NCT06292897 · Data updated 2026-11-12

This study looks at how being overweight or obese affects prostate cancer by checking certain enzymes and immune cells in tumor samples from patients with different body weights.

Quick facts

Study typeObservational
Ages18 Years and up
SexMen only
Enrollment25 (estimated)
SponsorFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Academic / other
Locations1 site (Milan)
StatusRecruiting
StartedMarch 20, 2023
Main results expectedSeptember 15, 2026
Study endsJanuary 15, 2027
Registry record updatedMarch 5, 2024
Trial IDNCT06292897 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with prostate cancer, particularly those with a BMI greater than 27.5.

Probably not a fit

Patients who are not affected by prostate cancer or have a BMI less than or equal to 27.5 may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the expression of lactate dehydrogenase enzyme (LDHA) and MCT-1/-4 transporters in prostate cancer tissues from patients with varying body mass indices (BMI). It aims to characterize the immune cell presence in these tumors and assess how lactate accumulation relates to changes in the tumor immune environment and oncogenic pathways. By comparing severely overweight/obese patients to those with normal weight, the study seeks to uncover metabolic influences on cancer progression.

Why it matters

Potential benefit: If successful, this study could provide insights into how obesity impacts prostate cancer progression, potentially leading to targeted therapies.

How similar studies have gone: While the specific approach of this study may be novel, similar studies have explored the relationship between obesity and cancer progression, indicating potential for meaningful findings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* affected by prostate cancer

Exclusion Criteria:

\-

Where it's running

  • IRCCS Cà Granda Ospedale Maggiore Policlinico Milano
    Milan, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.