Understanding how light and meal timing affect body clocks in humans
Biomarkers for Peripheral Circadian Clocks in Humans
This study is testing how different light exposure and meal times affect our body clocks to help find new ways to improve health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 14 (estimated) |
| Ages | 17 Years to 35 Years |
| Sex | All |
| Sponsor | University of Colorado, Boulder Academic / other |
| Locations | 1 site (Boulder, Colorado) |
| Trial ID | NCT06296823 on ClinicalTrials.gov |
What this trial studies
This project aims to enhance our understanding of peripheral circadian rhythms in humans by utilizing simulated jetlag protocols. Participants will undergo a series of visits where they will maintain a regular sleep-wake schedule, wear activity and light exposure monitors, and consume controlled meals at specific times. The study will assess how variations in light exposure and meal timing influence blood and saliva proteins related to circadian rhythms. The ultimate goal is to identify new biomarkers for peripheral rhythms and develop circadian-based treatments.
Who should consider this trial
Good fit: Ideal candidates are healthy individuals aged 17-35 who reside at Denver altitude or higher.
Not a fit: Patients with medical, psychiatric, or sleep disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to novel treatments for aligning peripheral circadian rhythms, potentially improving health and well-being.
How similar studies have performed: Other studies have shown promise in understanding circadian rhythms, but this approach is novel in its focus on peripheral biomarkers.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1\) 17-35 years old 2) English speaking 3) Healthy 5) Altitude history: Currently residing at Denver altitude or higher Exclusion Criteria: 1\. Any medical, psychiatric, or sleep disorder.
Where this trial is running
Boulder, Colorado
- Sleep and Chronobiology Laboratory — Boulder, Colorado, United States (Recruiting)
Study contacts
- Study coordinator: Kenneth Wright, PhD
- Email: sleep.study@colorado.edu
- Phone: 303-735-1923
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.