Understanding how inflammation affects heart and metabolic health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between inflammatory resolution and cardiometabolic health in individuals with varying body mass indices (BMIs). Participants will include lean, overweight, and obese volunteers who meet specific eligibility criteria. The study will assess how inflammation impacts health outcomes in these groups, focusing on their metabolic profiles and cardiovascular health. Data will be collected through blood draws and health assessments to analyze the effects of inflammation on cardiometabolic conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Informed signed consent has been obtained from the volunteer.
* The volunteer has a BMI greater than 18.5 kg/m2

Exclusion Criteria:

* The study staff contacting a potential participant perceives that the individual has difficulty understanding the information.
* An MD determines that the individual is on too many medications to participate
* The individual takes a medication that is approved by the MD, but he/she is not willing or not able to wait with any potential morning medication until after their fasted blood-draw.
* The individual is younger than 18 years (relevant for the FAINT-1 and FAINT-2 cohorts)
* The individual states that they have increased bleeding tendency or are using anti-coagulant (blood thinning) medication.
* The individual has some form of chronic inflammation.
* The individual regularly uses medication that affects inflammatory resolution (e.g., low-dose aspirin).
* The individual uses immunosuppressive drugs (eg, methotrexate).
* The individual regularly consumes fish oils (omega 3).
* The individual has significant gastrointestinal problems.
* The individual smokes or uses chewing tobacco.
* The individual has been drinking alcohol two days before the study visit.
* The individual has tattoos or body piercings on the forearms and / or the stomach that can affect the examination.
* The individual does not follow instructions given in the research study.

Where it's running

• Gothenburg university
  Gothenburg, Västra Götaland County, Sweden Recruiting

Study contacts

• Study coordinator: Emma Börgeson, PhD
• Email: emma.borgeson@wlab.gu.se
• Phone: +46313423833

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.