Understanding how gut bacteria can help diagnose colorectal cancer
A Multi-center Study on Human Microecology Assisted Diagnosis of Colorectal Cancer
This study is trying to see if the types of bacteria in the gut can help doctors better diagnose colorectal cancer in patients undergoing colonoscopy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5 (estimated) |
| Sex | All |
| Sponsor | Zhujiang Hospital Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT05998915 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the distribution characteristics of intestinal microecology, including flora and peptidoglycan fragments, in patients with colorectal diseases. By analyzing these microbial patterns, the study seeks to determine their potential as prognostic indicators for disease development. Participants will be observed during their scheduled colonoscopy examinations, with no interventions applied. The findings could enhance diagnostic accuracy and improve patient outcomes in colorectal cancer.
Who should consider this trial
Good fit: Ideal candidates are individuals scheduled for a colonoscopy examination.
Not a fit: Patients diagnosed with other cancers or those who have recently taken antibiotics or laxatives may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic methods for colorectal cancer based on gut microbiome analysis.
How similar studies have performed: While the concept of using gut microbiome for diagnostic purposes is gaining traction, this specific approach is relatively novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * people who is going to get the colonoscopy examination Exclusion Criteria: * people who was diagnosed as one cancer，expect for CRC; who has had the antibiotics or the medicine that treats for colorectal disease, except for medical probiotics, in one month; who has had the laxative and the colonscopy in one week; who had a operation in three month.
Where this trial is running
Guangzhou, Guangdong
- Zhujiang Hospital of Southern Medical University — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: 钟 典
- Email: vmojito@163.com
- Phone: 18928794133
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.