Understanding how exercise affects fitness in different adults
Response Variability to Exercise in Adults
This study is testing if different levels of exercise can help adults who don’t see benefits from regular workouts improve their heart and lung fitness.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 25 Years to 65 Years |
| Sex | All |
| Sponsor | Queen's University Academic / other |
| Locations | 1 site (Kingston, Ontario) |
| Trial ID | NCT05496751 on ClinicalTrials.gov |
What this trial studies
This study investigates the variability in response to exercise among adults, challenging the notion that all individuals benefit equally from physical activity guidelines. It aims to determine if increasing exercise intensity or amount can improve cardiorespiratory fitness (CRF) in those who do not respond to standard exercise recommendations. The trial will involve a 16-week intervention with different exercise regimens to assess changes in CRF and associated cardiometabolic risk factors. The findings could reshape how healthcare practitioners approach exercise prescriptions for diverse populations.
Who should consider this trial
Good fit: Ideal candidates are sedentary adults with a stable weight and a BMI between 20 and 40 kg/m2.
Not a fit: Patients with physical impairments, diabetes, or those planning to relocate within the next eight months may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more personalized exercise recommendations that better address individual fitness responses and health outcomes.
How similar studies have performed: While the approach of examining individual variability in exercise response is gaining attention, this specific investigation into resistance to exercise benefits is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Sedentary lifestyle (planned physical activity for one day per week or less). * Weight stable (± 2 kg) for 6 months prior to the beginning of the study. * BMI between 20 and 40 kg/m2. Exclusion Criteria: * Physical impairment which would make the intervention very difficult or unsafe according to doctor's advice. * Diabetes, current smokers. * Plan to move from the area in next 8 months.
Where this trial is running
Kingston, Ontario
- School of Kinesiology and Health Studies, Queen's University — Kingston, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Robert Ross, PhD — Queen's University
- Study coordinator: Robert Ross, PhD
- Email: rossr@queensu.ca
- Phone: 613-533-6583
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.