Understanding how emotions and motivation affect cognition in schizophrenia

Influence of Emotion and Motivation on Behaviour and Neural Activity in Patients With Psychosis

Not applicable Interventional University Hospital, Strasbourg, France · NCT02853019

This study is trying to see how feelings and motivation problems affect thinking in people with schizophrenia to find better ways to help them.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 55 Years
SexAll
SponsorUniversity Hospital, Strasbourg, France Academic / other
Locations1 site (Strasbourg)
Trial IDNCT02853019 on ClinicalTrials.gov

What this trial studies

This study investigates the roles of emotional and motivational disorders, specifically anhedonia and avolition, in patients with schizophrenia. It aims to explore the cognitive and neuronal mechanisms underlying these disorders and how they influence cognitive functions. The methodology includes the use of electroencephalograms, cognitive tasks, and subjective evaluation scales to gather data on the participants' experiences and responses. By gaining insights into these mechanisms, the study seeks to improve understanding and treatment of schizophrenia symptoms.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with schizophrenia according to the DSM criteria.

Not a fit: Patients with addiction issues, significant visual sensory problems, or a neurological history may not benefit from this study.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for emotional and motivational symptoms in schizophrenia.

How similar studies have performed: While the specific approach of this study may be novel, previous research has indicated the importance of understanding emotional and motivational factors in schizophrenia, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diagnostic and Statistical Manual of Mental Disorders criteria for schizophrenia

Exclusion Criteria:

* addiction problem
* invalidating visual sensory problems
* neurological history
* for the healthy volunteers: psychiatric history

Where this trial is running

Strasbourg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions SchizophreniaEmotionmotivationcognitionschizophrenia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.